ID A0A0D9R1P4_CHLSB Unreviewed; 641 AA.
AC A0A0D9R1P4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Zona pellucida glycoprotein 1 {ECO:0000313|Ensembl:ENSCSAP00000002533.1};
GN Name=ZP1 {ECO:0000313|Ensembl:ENSCSAP00000002533.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000002533.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000002533.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000002533.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}. Zona pellucida
CC {ECO:0000256|ARBA:ARBA00024183}.
CC -!- SIMILARITY: Belongs to the ZP domain family. ZPB subfamily.
CC {ECO:0000256|ARBA:ARBA00010863}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00779}.
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DR EMBL; AQIB01079331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01079332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01079333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01079334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01079335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01079336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9R1P4; -.
DR STRING; 60711.ENSCSAP00000002533; -.
DR Ensembl; ENSCSAT00000004275.1; ENSCSAP00000002533.1; ENSCSAG00000006244.1.
DR eggNOG; ENOG502RYNN; Eukaryota.
DR GeneTree; ENSGT00940000161188; -.
DR OMA; RFEVNNC; -.
DR Proteomes; UP000029965; Chromosome 1.
DR Bgee; ENSCSAG00000006244; Expressed in pituitary gland.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:Ensembl.
DR GO; GO:0035805; C:egg coat; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR CDD; cd00111; Trefoil; 1.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR017957; P_trefoil_CS.
DR InterPro; IPR000519; P_trefoil_dom.
DR InterPro; IPR044913; P_trefoil_dom_sf.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR048290; ZP_chr.
DR InterPro; IPR001507; ZP_dom.
DR InterPro; IPR017977; ZP_dom_CS.
DR PANTHER; PTHR23343; ZONA PELLUCIDA SPERM-BINDING PROTEIN; 1.
DR PANTHER; PTHR23343:SF41; ZONA PELLUCIDA SPERM-BINDING PROTEIN 1; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR PRINTS; PR00023; ZPELLUCIDA.
DR SMART; SM00018; PD; 1.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57492; Trefoil; 1.
DR PROSITE; PS00025; P_TREFOIL_1; 1.
DR PROSITE; PS51448; P_TREFOIL_2; 1.
DR PROSITE; PS00682; ZP_1; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00779}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Fertilization {ECO:0000256|ARBA:ARBA00023279};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..641
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002344239"
FT TRANSMEM 605..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 237..277
FT /note="P-type"
FT /evidence="ECO:0000259|PROSITE:PS51448"
FT DOMAIN 282..556
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 141..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 248..263
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00779"
SQ SEQUENCE 641 AA; 70453 MW; 17CFFAA47323BA57 CRC64;
MAGGSATTWG YRVALLLLVA TLGLGRRLQP DPGLPGLRHS YDCGIKGMQL LVFPRPGQTL
RFKVVDEFGN RFDVNNCSIC YHWVTSRPQE PAVFSADYRG CHVLEKNGRF HLRVFMEAVL
PDGHVDVAQD TTLICPKPDH SWTPDSQLAP PTMFSVSTPQ TLPSLPTSGH TSPGSGHAFP
SPFPLDPGHS SVHPTPALPS PGPGPALATL AQHHRGPLEH WDVNKPDYMT CTHLSQEQCQ
VASGHLPCIV RRTSKEACQR AGCCYDNTRE VPCYYGNTAT LQCFRDGYFI LVVSQEVALT
HRITLANVHL AYAPTSCSPT QHTEAFVVFY FPLSHCGTTV QVAGDQLIYE NWLVSGIHVR
KGPQGSITRD STFQLHVRCV FNASDFLPIR ASIYPPLSPA PVTQPGPLRL ELRIAKDETF
SSYYGEDDYP IVRLLREPVH VEVRLLQRTD PNLVLLLHQC WGAPSANPFQ QPQWPILSDG
CPFEGDSYRT QMVALDGATP FQSHYQRFTV ATFALLDSGS QRALRGPVYL FCSASACHTS
GLETCSSVCS AGTARQRRSS GHRNDTARPQ DIVSSPGPVG FEDSYGQEPT LGPTDSNGNS
SLRPLLWMVL LLPAVALVLG FGVFVGLSQT WVQKLWENSE W
//
