ID A0A0D9R1X0_CHLSB Unreviewed; 328 AA.
AC A0A0D9R1X0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA repair protein {ECO:0000256|PIRNR:PIRNR005856};
GN Name=RAD51D {ECO:0000313|Ensembl:ENSCSAP00000002609.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000002609.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000002609.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000002609.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the homologous recombination repair (HRR) pathway
CC of double-stranded DNA breaks arising during DNA replication or induced
CC by DNA-damaging agents. {ECO:0000256|PIRNR:PIRNR005856}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005856}.
CC -!- SIMILARITY: Belongs to the RecA family. RAD51 subfamily.
CC {ECO:0000256|PIRNR:PIRNR005856}.
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DR EMBL; AQIB01146960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9R1X0; -.
DR STRING; 60711.ENSCSAP00000002609; -.
DR Ensembl; ENSCSAT00000004354.1; ENSCSAP00000002609.1; ENSCSAG00000006316.1.
DR eggNOG; KOG1433; Eukaryota.
DR GeneTree; ENSGT00940000159095; -.
DR OMA; QRIHTFR; -.
DR OrthoDB; 11612at2759; -.
DR Proteomes; UP000029965; Chromosome 16.
DR Bgee; ENSCSAG00000006316; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl.
DR GO; GO:0033063; C:Rad51B-Rad51C-Rad51D-XRCC2 complex; IEA:Ensembl.
DR GO; GO:0005657; C:replication fork; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:Ensembl.
DR GO; GO:0000400; F:four-way junction DNA binding; IEA:Ensembl.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:Ensembl.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0042148; P:DNA strand invasion; IEA:Ensembl.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR GO; GO:0000722; P:telomere maintenance via recombination; IEA:Ensembl.
DR CDD; cd19489; Rad51D; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047323; Rad51D_C.
DR InterPro; IPR048943; RAD51D_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR46457; DNA REPAIR PROTEIN RAD51 HOMOLOG 4; 1.
DR PANTHER; PTHR46457:SF1; DNA REPAIR PROTEIN RAD51 HOMOLOG 4; 1.
DR Pfam; PF08423; Rad51; 1.
DR Pfam; PF21794; RAD51D_N; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00023204};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005856};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 78..251
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 328 AA; 35107 MW; 726084CA3EB572DB CRC64;
MGVLRVGLCP GLTQEMIQLL RSRRIKTVVD LVSADLEEVA QKCGLSYKAL VALRRVLLAQ
FSAFPLNGAD LYEELKTSTA ILSTGIGSLD KLLDAGLYTG EVTEIVGGPG SGKTQVCLCV
AANVAHGLQQ NVLYVDSNGG LTASRLLQLL QTKTQDEEEQ AEALQRIQVV HAFDIFQMLD
VLQELRGTVA QQVTGSSGTM KVVVVDSVTA VVSPLLGGQQ REGLALMMQL ARELKTLARD
LGMAVVVTNH ITRDRDSGRL KPALGRSWSF VPSTRILLDA IEGAGASAGR RMACLTKSPR
QPTGFQEMVD IGTWGTSEQS ATLQGDQT
//
