ID A0A0D9R3A6_CHLSB Unreviewed; 452 AA.
AC A0A0D9R3A6;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Phospholipid phosphatase related 2 {ECO:0000313|Ensembl:ENSCSAP00000003095.1};
GN Name=PLPPR2 {ECO:0000313|Ensembl:ENSCSAP00000003095.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000003095.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000003095.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000003095.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000256|ARBA:ARBA00008816}.
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DR EMBL; AQIB01140941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007993483.1; XM_007995292.1.
DR AlphaFoldDB; A0A0D9R3A6; -.
DR STRING; 60711.ENSCSAP00000003095; -.
DR Ensembl; ENSCSAT00000004854.1; ENSCSAP00000003095.1; ENSCSAG00000006808.1.
DR GeneID; 103233923; -.
DR KEGG; csab:103233923; -.
DR CTD; 64748; -.
DR eggNOG; KOG3030; Eukaryota.
DR GeneTree; ENSGT00940000158145; -.
DR OMA; IISGACC; -.
DR OrthoDB; 25293at2759; -.
DR BioGRID-ORCS; 103233923; 0 hits in 8 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 6.
DR Bgee; ENSCSAG00000006808; Expressed in Ammon's horn and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR CDD; cd03384; PAP2_wunen; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; LIPID PHOSPHATE PHOSPHATASE; 1.
DR PANTHER; PTHR10165:SF15; PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 130..281
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
FT REGION 320..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..401
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 48400 MW; 14CDF140DB314C67 CRC64;
MAGGRPHLKR SFSIIPCFVF VESVLLGIVI LLAYRLEFTD TFPVHTQGFF CYDSTYAKPY
PGPEAASRVP PALIYALVTA GPTLTILLGE LARAFFPAPP SAVPVIGEST IVSGACCRFS
PPLRRLVRFL GVYSFGLFTT TIFANAGQVV TGNPTPHFLS VCRPNYTALG CLPPSPDRPG
PDRFVTDQGA CAGSPSLVAA ARRAFPCKDA ALCAYAVTYT AMYVTLVFRV KGSRLVKPSL
CLALLCPAFL VGVVRVAEYR NHWSDVLAGF LTGAAIATFL VTCVVHNFQS RPPSGRRLSP
WEDLGQAPTV DSPLEKLSVA QEPEVCRPHS TPARLTPSKS QNCARRGHLI PSCVSSRAPA
MCSSPRVPRP RLRSEPTPLP LPLPLPAPTP SQGPSPSSPG PGGPGGGGGR GRKLLLPTPL
LRDLYTLSGL YPSPFHRDNF SPYLFASRDH LL
//
