ID A0A0D9R453_CHLSB Unreviewed; 200 AA.
AC A0A0D9R453;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Integrin subunit beta 1 binding protein 1 {ECO:0000313|Ensembl:ENSCSAP00000003392.1};
GN Name=ITGB1BP1 {ECO:0000313|Ensembl:ENSCSAP00000003392.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000003392.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000003392.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000003392.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01030550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01030551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01030552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01030553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007969714.1; XM_007971523.1.
DR RefSeq; XP_007969716.1; XM_007971525.1.
DR RefSeq; XP_007969717.1; XM_007971526.1.
DR RefSeq; XP_007969718.1; XM_007971527.1.
DR RefSeq; XP_007969719.1; XM_007971528.1.
DR AlphaFoldDB; A0A0D9R453; -.
DR STRING; 60711.ENSCSAP00000003392; -.
DR Ensembl; ENSCSAT00000005161.1; ENSCSAP00000003392.1; ENSCSAG00000007115.1.
DR GeneID; 103220848; -.
DR KEGG; csab:103220848; -.
DR CTD; 9270; -.
DR eggNOG; ENOG502QS6V; Eukaryota.
DR GeneTree; ENSGT00390000003990; -.
DR OMA; QCHSLEQ; -.
DR OrthoDB; 4183974at2759; -.
DR BioGRID-ORCS; 103220848; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 14.
DR Bgee; ENSCSAG00000007115; Expressed in caudate nucleus and 7 other cell types or tissues.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030027; C:lamellipodium; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0001726; C:ruffle; IEA:Ensembl.
DR GO; GO:0005092; F:GDP-dissociation inhibitor activity; IEA:Ensembl.
DR GO; GO:0005178; F:integrin binding; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0097746; P:blood vessel diameter maintenance; IEA:Ensembl.
DR GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IEA:Ensembl.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEA:Ensembl.
DR GO; GO:0033622; P:integrin activation; IEA:Ensembl.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0051451; P:myoblast migration; IEA:Ensembl.
DR GO; GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IEA:Ensembl.
DR GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IEA:Ensembl.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR GO; GO:0010764; P:negative regulation of fibroblast migration; IEA:Ensembl.
DR GO; GO:0051895; P:negative regulation of focal adhesion assembly; IEA:Ensembl.
DR GO; GO:0090315; P:negative regulation of protein targeting to membrane; IEA:Ensembl.
DR GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl.
DR GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR GO; GO:0051897; P:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; IEA:Ensembl.
DR GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IEA:Ensembl.
DR GO; GO:2001044; P:regulation of integrin-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0035148; P:tube formation; IEA:Ensembl.
DR CDD; cd13163; PTB_ICAP1; 1.
DR Gene3D; 6.20.360.10; -; 1.
DR InterPro; IPR019517; Integrin-bd_ICAP-1.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR32055; INTEGRIN BETA-1-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR32055:SF1; INTEGRIN BETA-1-BINDING PROTEIN 1; 1.
DR Pfam; PF10480; ICAP-1_inte_bdg; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 58..200
FT /note="PID"
FT /evidence="ECO:0000259|SMART:SM00462"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 200 AA; 21766 MW; 0F041238F055BE23 CRC64;
MFRKGKKRHS SSSSQSSEIS TKSKSVDSSL GGLSRSSTVA SLDTDSTKSS GQSNNNSDTC
AEFRIKYVGA IEKLKLSEGK GLEGPLDLIN YIDVAQQDGK LPFVPPEEEF IMGVSKYGIK
VSTSDQYDVL HRHALYLIIR MVCYDDGLGA GKSLLALKTT DASNEEYSLW VYQCNSLEQA
QAICKVLATA FDSVLTSEKP
//
