ID A0A0D9R478_CHLSB Unreviewed; 128 AA.
AC A0A0D9R478;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 {ECO:0000256|ARBA:ARBA00018681};
DE AltName: Full=Complex I-B15 {ECO:0000256|ARBA:ARBA00030212};
DE AltName: Full=NADH-ubiquinone oxidoreductase B15 subunit {ECO:0000256|ARBA:ARBA00030987};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000003417.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000003417.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000003417.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004298}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004298}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004298}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB4 subunit family.
CC {ECO:0000256|ARBA:ARBA00007260}.
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DR EMBL; AQIB01110750; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01110751; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01110752; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01110753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007983858.1; XM_007985667.1.
DR AlphaFoldDB; A0A0D9R478; -.
DR STRING; 60711.ENSCSAP00000003417; -.
DR Ensembl; ENSCSAT00000005186.1; ENSCSAP00000003417.1; ENSCSAG00000007142.1.
DR GeneID; 103228205; -.
DR KEGG; csab:103228205; -.
DR CTD; 4710; -.
DR eggNOG; ENOG502S2HF; Eukaryota.
DR GeneTree; ENSGT00390000007133; -.
DR OMA; REYLLHY; -.
DR OrthoDB; 5343231at2759; -.
DR BioGRID-ORCS; 103228205; 2 hits in 14 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 22.
DR Bgee; ENSCSAG00000007142; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009866; NADH_UbQ_OxRdtase_NDUFB4_su.
DR PANTHER; PTHR15469:SF0; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR15469; NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT; 1.
DR Pfam; PF07225; NDUF_B4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 86..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 128 AA; 14846 MW; 26B4EF6722B0F455 CRC64;
MSTSKYKPSH LATLPSTLDP AEYDTSPETR RAQAERLAIR ARLKREYLLQ YNDPNRRGLI
ENPALLRWTY ARTNVYPNFR PTPKNSLMGA VFGIGPLIFL YCVIKADRDR KEKLIREGKL
DRTFQLSC
//
