ID A0A0D9R6T0_CHLSB Unreviewed; 486 AA.
AC A0A0D9R6T0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Matrilin 3 {ECO:0000313|Ensembl:ENSCSAP00000004319.1};
GN Name=MATN3 {ECO:0000313|Ensembl:ENSCSAP00000004319.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000004319.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000004319.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000004319.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AQIB01032354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032362; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01032363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007969564.1; XM_007971373.1.
DR RefSeq; XP_007969565.1; XM_007971374.1.
DR AlphaFoldDB; A0A0D9R6T0; -.
DR STRING; 60711.ENSCSAP00000004319; -.
DR Ensembl; ENSCSAT00000006110.1; ENSCSAP00000004319.1; ENSCSAG00000008064.1.
DR KEGG; csab:103220727; -.
DR eggNOG; KOG1217; Eukaryota.
DR GeneTree; ENSGT00940000157581; -.
DR OMA; CALGTHQ; -.
DR OrthoDB; 1453590at2759; -.
DR BioGRID-ORCS; 103220727; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 14.
DR Bgee; ENSCSAG00000008064; Expressed in fibroblast and 4 other cell types or tissues.
DR GO; GO:0120216; C:matrilin complex; IEA:Ensembl.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF12; MATRILIN-3; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..486
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002344661"
FT DOMAIN 83..258
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 264..305
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 306..347
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 348..389
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 36..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 52707 MW; EAED27F89642B266 CRC64;
MPRPAPARRL PGLLLLLWPL LLLPLAAPDP VARPGFRRLG TRGPEGSPGR RPSSVAPDGA
PASGASEPGR ASGAGVCKSR PLDLVFLIDS SRSVRPLEFT KVKTFVSRII DTLDIGPADT
RVAVVNYAST VKIEFQLQAY TDKQSLKQAV GRITPLSTGT MSGLAIQTAM DEVFTVEAGA
RGPSSNIPKV AIIVTDGRPQ DQVNEVAARA RASGIELYAV GVDRADMESL KMMASEPLEE
HVFYVETYGV IEKLSSRFQE TFCALDPCVL GTHQCQHVCI SDGEGKHHCE CSQGYTLNAD
KKTCSALDKC ALNIHGCEHI CVNDRSGSYH CECYEGYTLN EDRKTCSAQD KCALGTHGCQ
HICVNDRTGS YHCECYDGYT LNADKKTCSV RDKCALGSHG CEHICVSDGA ASYHCDCYPG
YTLNEDKKTC SAIEEARRLV STEDVCGCEA TLAFQEKVSS SLQRLNTKLD GILEKLQVNE
YGQIHR
//
