ID A0A0D9RH99_CHLSB Unreviewed; 381 AA.
AC A0A0D9RH99;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Actin binding Rho activating protein {ECO:0000313|Ensembl:ENSCSAP00000007988.1};
GN Name=ABRA {ECO:0000313|Ensembl:ENSCSAP00000007988.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000007988.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000007988.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000007988.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01114811; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007999537.1; XM_008001346.1.
DR AlphaFoldDB; A0A0D9RH99; -.
DR STRING; 60711.ENSCSAP00000007988; -.
DR Ensembl; ENSCSAT00000009880.1; ENSCSAP00000007988.1; ENSCSAG00000011785.1.
DR GeneID; 103237277; -.
DR KEGG; csab:103237277; -.
DR CTD; 137735; -.
DR eggNOG; KOG3376; Eukaryota.
DR GeneTree; ENSGT00390000015984; -.
DR OMA; DEPKWRS; -.
DR OrthoDB; 4166202at2759; -.
DR BioGRID-ORCS; 103237277; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 8.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:Ensembl.
DR GO; GO:0030016; C:myofibril; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003779; F:actin binding; IEA:Ensembl.
DR GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 1.10.10.1540; Costar domain; 1.
DR InterPro; IPR026111; Abra.
DR InterPro; IPR027817; Costars_dom.
DR InterPro; IPR038095; Costars_sf.
DR PANTHER; PTHR22739:SF20; ACTIN-BINDING RHO-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR22739; STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED; 1.
DR Pfam; PF14705; Costars; 1.
DR SMART; SM01283; Costars; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 304..380
FT /note="Costars"
FT /evidence="ECO:0000259|SMART:SM01283"
FT REGION 39..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 43294 MW; 1123E207A4B0A0DB CRC64;
MAPGEKEREE APAKSALRKI RTATLVINLA RGWQQWANEN SIKQAQEPTG WLPGGTQDSP
QAPKPITPPT SHQKAQSAPK SPPRTPEGHG DGQSSEKAPE VSHIKKKEVT KTVVSKAYER
GGDVSHLSHR YERDVGVPEP GQPENDIDRI LHSHGSPTRR RKCANLVSEL TKGWRVMEQE
EPTWRSDSVD TEDSGYGGEA EERPEQDGVQ VAVARIKRPL PSQVNRFTEK LNCKAQQKYS
QVGNLKGRWQ QWADEHIQSQ KLNPFSEEFD YELAMSTRLH KGDEGYGRPK EGTKTAERAK
RAEEHIYREI MDMCFIIRTM ARHRRDGKIQ VTFGDLFDRY VRISDKVVGI LMRARKHGLV
DFEGEMLWQG RDDHVVITLL K
//
