ID A0A0D9RHU4_CHLSB Unreviewed; 481 AA.
AC A0A0D9RHU4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=ADAMTS like 5 {ECO:0000313|Ensembl:ENSCSAP00000008183.1};
GN Name=ADAMTSL5 {ECO:0000313|Ensembl:ENSCSAP00000008183.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000008183.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000008183.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000008183.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AQIB01152656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007992820.1; XM_007994629.1.
DR RefSeq; XP_007992821.1; XM_007994630.1.
DR RefSeq; XP_007992822.1; XM_007994631.1.
DR AlphaFoldDB; A0A0D9RHU4; -.
DR STRING; 60711.ENSCSAP00000008183; -.
DR Ensembl; ENSCSAT00000010084.1; ENSCSAP00000008183.1; ENSCSAG00000012011.1.
DR GeneID; 103233612; -.
DR CTD; 339366; -.
DR eggNOG; KOG3538; Eukaryota.
DR GeneTree; ENSGT00940000160456; -.
DR OMA; WAPGRCP; -.
DR OrthoDB; 2941362at2759; -.
DR BioGRID-ORCS; 103233612; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 6.
DR Bgee; ENSCSAG00000012011; Expressed in fibroblast and 5 other cell types or tissues.
DR GO; GO:0031012; C:extracellular matrix; IEA:Ensembl.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd03523; NTR_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF173; ADAMTS-LIKE PROTEIN 5; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF01759; NTR; 1.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS50189; NTR; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..42
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 43..481
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002345091"
FT DOMAIN 360..479
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT DISULFID 57..91
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 61..96
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 72..81
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 481 AA; 53200 MW; 725C547AD82272A4 CRC64;
MGKLRPGRVE WLASGHTERP CLFQNLLLLL WALLNCGLGV SAQGPGEWTP WVSWTRCSSS
CGRGVSVRSR RCLRLPGEDP CWGDSHEYRL CQLPDCPPGA VPFRDLQCAL YNGRPVLGTQ
KTYQWVPFHG APNQCDLNCL AEGHAFYHSF GRVLDGTACS PGAQGVCVAG RCLSPGCDGL
LGSGALEDRC GRCGGANDSC LFVQRVFRDA GAFAGYWNVT LIPEGARHIR VAHRSRNHLA
LMGGDGRYVL NGDWVVSPPG TYEAAGTHVV YTRDAGPQET LQAAGPTSHN LLLQVLLQEP
NPGIEFEFWL PQERYSPFQA RVQALGWPLR QPQPREVEPQ PPAAPAVIPA RTPTLAPDPC
PPCPDTRGRA HRLLHYCGSD FVFQARVLGR HRQAQETRYE VRIQLVYKNR SPLRAREYVW
APGHCPCPML APHRDYLLAV QRLVSPNGTQ DRLLLPHAGY ARPWSPAEDS RVRLTARRCP
I
//
