ID A0A0D9RJN1_CHLSB Unreviewed; 594 AA.
AC A0A0D9RJN1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Metastasis associated 1 family member 3 {ECO:0000313|Ensembl:ENSCSAP00000008820.1};
GN Name=MTA3 {ECO:0000313|Ensembl:ENSCSAP00000008820.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000008820.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000008820.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000008820.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01037789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037794; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01037798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007969011.1; XM_007970820.1.
DR AlphaFoldDB; A0A0D9RJN1; -.
DR STRING; 60711.ENSCSAP00000008820; -.
DR Ensembl; ENSCSAT00000010730.1; ENSCSAP00000008820.1; ENSCSAG00000012640.1.
DR eggNOG; KOG3554; Eukaryota.
DR GeneTree; ENSGT01030000234573; -.
DR OMA; HASQELD; -.
DR OrthoDB; 12566at2759; -.
DR BioGRID-ORCS; 103220403; 1 hit in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 14.
DR Bgee; ENSCSAG00000012640; Expressed in Ammon's horn and 7 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0016581; C:NuRD complex; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:1990739; P:granulosa cell proliferation; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:1904197; P:positive regulation of granulosa cell proliferation; IEA:Ensembl.
DR CDD; cd04709; BAH_MTA; 1.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF6; METASTASIS-ASSOCIATED PROTEIN MTA3; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 4..147
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 148..259
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 266..318
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
SQ SEQUENCE 594 AA; 67464 MW; CF81768C4BEB84E8 CRC64;
MAANMYRVGD YVYFENSSSN PYLIRRIEEL NKTASGNVEA KVVCFYRRRD ISNTLIMLAD
KHAKEIEEES ETTVEADLTD KQKHQLKHRE LFLSRQYESL PATHIRGKCS VALLNETESV
LSYLDKEDTF FYSLVYDPSL KTLLADKGEI RVGPRYQADI PEMLLEGESD EREQSKLEVK
VWDPNSPLTD RQIDQFLVVA RAVGTFARAL DCSSSVRQPS LHMSAAAASR DITLFHAMDT
LYRHSYDLSS AISVLVPLGG PVLCRDEMEE WSASEASLFE EALEKYGKDF NDIRQDFLPW
KSLTSIIEYY YMWKTTDRYV QQKRLKAAEA ESKLKQVYIP TYKPNPNQIS TSNGKPGAVN
GAVGTTFQPQ NPLLGRACES CYATQSHQWY SWGPPNMQCR LCAICWLYWK KYGGLKMPTQ
SEEEKLSPSP TTEDPRVRSH VSRQAMQGMP VRNTGSPKSA VKTRQAFFLH TTYFTKFARQ
VCKNTLRLRQ AARRPFVAIN YAAIRAEYAD RHAELSGSPL KSKSTRKPLA CIIGYLEIHP
AKKPNVIRST PSLQTPTTKR MLTTPNHTSL SILGKRNYSH HNGLDGNAED LGKL
//
