ID A0A0D9RPB1_CHLSB Unreviewed; 748 AA.
AC A0A0D9RPB1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Semaphorin 3B {ECO:0000313|Ensembl:ENSCSAP00000010450.1};
GN Name=SEMA3B {ECO:0000313|Ensembl:ENSCSAP00000010450.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000010450.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000010450.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000010450.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
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DR EMBL; AQIB01131909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007982492.1; XM_007984301.1.
DR RefSeq; XP_007982493.1; XM_007984302.1.
DR AlphaFoldDB; A0A0D9RPB1; -.
DR STRING; 60711.ENSCSAP00000010450; -.
DR Ensembl; ENSCSAT00000012412.1; ENSCSAP00000010450.1; ENSCSAG00000014316.1.
DR GeneID; 103227665; -.
DR CTD; 7869; -.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000157756; -.
DR OMA; ISLHRCA; -.
DR OrthoDB; 5342713at2759; -.
DR BioGRID-ORCS; 103227665; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 22.
DR Bgee; ENSCSAG00000014316; Expressed in pituitary gland and 5 other cell types or tissues.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF37; SEMAPHORIN-3B; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00352};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..748
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002345544"
FT DOMAIN 30..512
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 572..658
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 700..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 102..113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00352"
FT DISULFID 131..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00352"
FT DISULFID 269..379
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00352"
FT DISULFID 293..339
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00352"
SQ SEQUENCE 748 AA; 83161 MW; E701FA9E1BC59622 CRC64;
MGRAGAAAMI PGLALLWAVG LGGAAPSPPR LRLSFQELQA WHGLQTFSLE RTCCYEALLV
DEERGRLFVG AENHVASLSL DNISKRAKKL AWPAPVEWRE ECNWAGKDIG TECMNFVKLL
HAYNRTHLLA CGTGAFHPTC AFVEVGHRAE EPVLRLDPGR IEDGKGKSPY DPRHRAASVL
VGEELYSGVA ADLMGRDFTI FRSLGQRPSL RTEPHDSRWL NEPKFVKVFW IPENENPDDD
KIYFFFRETA VEAAPVLGRL SVSRVGQICR NDVGGQRSLV NKWTTFLKAR LVCSVPGVEG
DTHFDQLQDV FLLSSRDHRT PLLYAVFSTS SIFQGSAVCV YSMNDVRRAF LGPFAHKEGP
MHQWVSYQGR VPYPRPGMCP SKTFGTFSST KDFPDDVIQF ARNHPLMYNS VLPIGGRPLF
LQVGANYTFT QIATDRVAAA DGHYDVLFIG TDAGTVLKVI SVPKGSRPSA EGLLLEELHV
FEDSAAVTSM QISSKRHQLY IASRSAVAQI ALHRCAAHGR VCAECCLARD PYCAWDGVAC
TRFQPSVKRR FRRQDVRNGD PSTLCSGDSS RPALLEHRVF GVEGSSAFLE CEPRSLQARV
EWTFQRAGVT THTQVLAQER TERTARGLLL RRLRRRDSGV YLCAAVEQGF TQPLRRLSLH
VLSATQAERL ARAEEAAPAA PPGPKLWYRD FLQLVEPGGG GSANSLRMCR PQPALQSLPP
ESRRKGRNRR THAPEPRAER GPRSVTHW
//
