ID A0A0D9RPE1_CHLSB Unreviewed; 413 AA.
AC A0A0D9RPE1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Double C2 domain beta {ECO:0000313|Ensembl:ENSCSAP00000010480.1};
GN Name=DOC2B {ECO:0000313|Ensembl:ENSCSAP00000010480.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000010480.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000010480.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000010480.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01154221; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01154222; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008007954.1; XM_008009763.1.
DR AlphaFoldDB; A0A0D9RPE1; -.
DR STRING; 60711.ENSCSAP00000010480; -.
DR Ensembl; ENSCSAT00000012444.1; ENSCSAP00000010480.1; ENSCSAG00000014361.1.
DR KEGG; csab:103242095; -.
DR eggNOG; KOG1013; Eukaryota.
DR GeneTree; ENSGT00940000156758; -.
DR OMA; HCTINRA; -.
DR OrthoDB; 590187at2759; -.
DR BioGRID-ORCS; 103242095; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 16.
DR Bgee; ENSCSAG00000014361; Expressed in Ammon's horn and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:UniProt.
DR CDD; cd04035; C2A_Rabphilin_Doc2; 1.
DR CDD; cd08384; C2B_Rabphilin_Doc2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR014638; Doc2.
DR InterPro; IPR043566; Rabphilin/DOC2/Noc2.
DR InterPro; IPR047022; Rabphilin_Doc2_C2A.
DR InterPro; IPR001565; Synaptotagmin.
DR PANTHER; PTHR45729:SF9; DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA; 1.
DR PANTHER; PTHR45729; RABPHILIN, ISOFORM A; 1.
DR Pfam; PF00168; C2; 2.
DR PIRSF; PIRSF036931; Doc2; 1.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 126..250
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 266..400
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 36..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 413 AA; 45934 MW; 4C30BCE3A16D657C CRC64;
MTLPRRGEKA TISIQEHMAI DVCPGPIRPI KQISDYFPRF PRGLPPDAGP RAAAPPDASA
RPAAASAGRR SPSDGAREDD EDVDQLFGAY GSSPGPSPGP SPARPPAKPP EDEPDADGYE
SDDCTALGTL DFSLLYDQEN NALHCTITKA KGLKPMDHNG LADPYVKLHL LPGASKANKL
RTKTLRNTLN PTWNETLTYY GITDEDMIRK TLRISVCDED KFRHNEFIGE TRVPLKKLKA
NHTKTFSICL EKQLPVDKTE DKSLEERGRI LISLKYSSQK QGLLVGIVRC AHLAAMDANG
YSDPYVKTYL RPDVDKKSKH KTAVKKKTLN PEFNEQEFCY EIKHGDLAKK SLEVTVWDYD
IGKSNDFIGG VVLGINAKGE RLKHWFDCLK NKDKRIERWH TLTSELPGAV LSD
//
