ID A0A0D9RQ36_CHLSB Unreviewed; 421 AA.
AC A0A0D9RQ36;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Ankyrin repeat and SOCS box containing 6 {ECO:0000313|Ensembl:ENSCSAP00000010725.1};
GN Name=ASB6 {ECO:0000313|Ensembl:ENSCSAP00000010725.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000010725.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000010725.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000010725.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR EMBL; AQIB01140380; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008004159.1; XM_008005968.1.
DR AlphaFoldDB; A0A0D9RQ36; -.
DR STRING; 60711.ENSCSAP00000010725; -.
DR Ensembl; ENSCSAT00000012695.1; ENSCSAP00000010725.1; ENSCSAG00000014602.1.
DR GeneID; 103239763; -.
DR KEGG; csab:103239763; -.
DR CTD; 140459; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00390000006784; -.
DR OMA; HLCRVHI; -.
DR OrthoDB; 5352456at2759; -.
DR UniPathway; UPA00143; -.
DR BioGRID-ORCS; 103239763; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 12.
DR Bgee; ENSCSAG00000014602; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03725; SOCS_ASB6; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037327; ASB6_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24132; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR PANTHER; PTHR24132:SF24; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 136..169
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 360..415
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 421 AA; 47183 MW; FB405EDC82CAECC7 CRC64;
MPFLHGFRRI IFEYQPLVDA ILGSLGIQDP ERQESLDRPS YVASEENRIL VLTELLERKA
HSPFYQEGVS NALLKMAELG LTQAADVLLR HGANLNFEDP VTYYTALHIA VLRNQPDMVE
LLVHHGADIN RRDRIHESSP LDLASEEPER LPCLQRLLDL GADVNAADKH GKTALLHALA
SSDGVQIHNT ENIRLLLEGG ADVKATTKDG DTVFTCIIFL LGETVGGDKE EAQMINRFCF
QVTRLLLAHG ADPSECPAHE SLTHICLKSF KLHFPLLRFL LESGAAYNCS LHGASCWSGF
HIVFERLCSH PGCTEDESHA DLLRKAETVL DLMVTNSQKL QLPENFDIHP VGSLAEKIQA
LHFSLRQLES YPPPLKHLCR VSIRLYLQPW PVDVKVKALP LPDRLKWYLL SEHSGSMEDD
I
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