ID A0A0D9RXK0_CHLSB Unreviewed; 347 AA.
AC A0A0D9RXK0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=SH3 domain containing GRB2 like 3, endophilin A3 {ECO:0000313|Ensembl:ENSCSAP00000013339.1};
GN Name=SH3GL3 {ECO:0000313|Ensembl:ENSCSAP00000013339.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000013339.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000013339.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000013339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR EMBL; AQIB01129013; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01129014; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007988401.1; XM_007990210.1.
DR AlphaFoldDB; A0A0D9RXK0; -.
DR STRING; 60711.ENSCSAP00000013339; -.
DR Ensembl; ENSCSAT00000015398.1; ENSCSAP00000013339.1; ENSCSAG00000017305.1.
DR GeneID; 103231077; -.
DR KEGG; csab:103231077; -.
DR CTD; 6457; -.
DR eggNOG; KOG1118; Eukaryota.
DR GeneTree; ENSGT00940000157398; -.
DR OMA; NFLENDX; -.
DR OrthoDB; 25371at2759; -.
DR BioGRID-ORCS; 103231077; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 29.
DR Bgee; ENSCSAG00000017305; Expressed in Ammon's horn and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd07615; BAR_Endophilin_A3; 1.
DR CDD; cd11803; SH3_Endophilin_A; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR032469; Endophilin-A3_BAR.
DR InterPro; IPR035824; Endophilin_A_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF45; ENDOPHILIN-A3; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 18..249
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 285..344
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 347 AA; 39213 MW; 66DE841A4FD69673 CRC64;
MSVAGLKKQF HKASQLFSEK ISGAEGTKLD DEFLDMERKI DVTNKAVAEI LSKTTEYLQP
NPAYRAKLGM LNTVSKIRGQ VKTTGYPQTE GLLGDCMLKY GKELGEDSTF GNALIEVGES
MKLMAEVKDS LDINVKQTFI DPLQLLQDKD LKEIGHHLKK LEGRRLDYDY KKKRVGKIPD
EEVRQAVEKF EESKELAERS MFNFLENDVE QVSQLAVFIE AALDYHKQST EILQELQSKL
QMRISAASSV PRREYKPRPV KRSASELNGV STTSVVKTTG SNIPMDQPCC RGLYDFEPEN
QGELGFKEGD IITLTNQIDE NWYEGMIHGE SGFFPINYVE VIVPLPQ
//
