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Database: UniProt
Entry: A0A0D9RZP7_CHLSB
LinkDB: A0A0D9RZP7_CHLSB
Original site: A0A0D9RZP7_CHLSB 
ID   A0A0D9RZP7_CHLSB        Unreviewed;       522 AA.
AC   A0A0D9RZP7;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   25-APR-2018, entry version 20.
DE   SubName: Full=SH2B adaptor protein 2 {ECO:0000313|Ensembl:ENSCSAP00000014086};
GN   Name=SH2B2 {ECO:0000313|Ensembl:ENSCSAP00000014086};
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000014086, ECO:0000313|Proteomes:UP000029965};
RN   [1] {ECO:0000313|Ensembl:ENSCSAP00000014086, ECO:0000313|Proteomes:UP000029965}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAP00000014086}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2015) to UniProtKB.
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DR   EMBL; AQIB01139540; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCSAT00000016165; ENSCSAP00000014086; ENSCSAG00000018067.
DR   GeneTree; ENSGT00530000063355; -.
DR   OMA; YDTEFFR; -.
DR   Proteomes; UP000029965; Chromosome 28.
DR   GO; GO:0005884; C:actin filament; IEA:Ensembl.
DR   GO; GO:0001726; C:ruffle; IEA:Ensembl.
DR   GO; GO:0001725; C:stress fiber; IEA:Ensembl.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IEA:Ensembl.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; IEA:Ensembl.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0050851; P:antigen receptor-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0001922; P:B-1 B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0019222; P:regulation of metabolic process; IEA:Ensembl.
DR   CDD; cd10411; SH2_SH2B2; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030520; SH2B2.
DR   InterPro; IPR035058; SH2B2_SH2.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF4; PTHR10872:SF4; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000029965};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      195    308       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      419    517       SH2. {ECO:0000259|PROSITE:PS50001}.
SQ   SEQUENCE   522 AA;  57062 MW;  4DDA9D3790984075 CRC64;
     MNGAAPGPAT AAPVPVPVPD WRQFCELHAQ AAAVDFAHKF CRFLRDNPAY DTPDAGASFS
     RHFAANFLDV FGEEVRRVLV AGPTTRGAAV RAEAMEPEPT DTSALKAAPY GHSRSSEDVS
     THAATKARVR KGFSLRNMSL CVVDGVRDMW HRRSSPEPEA GASLRAAEPS AEPRDKWTRR
     LRLSRTLAAK VELVDIQREG ALRFMVADDA AAGSGGSAQW QKCRLLLRRA VAEERFRLEF
     FVPPKASRPK VSIPLSAIIE VRTTMPLEMP EKDNTFVLKV ENGAEYILET IDSLQKHSWV
     ADIQGCVDPG DSEEDTELSC TRGGCLASRV ASCSCELLTD AVDLPRPPET TATGAVVTAP
     HSRGRDAVRE SLIHVPLETF LQTLESPGGS GSDSNNTGEE STETDPEAEP ELELSDYPWF
     HGTLSRVKAA QLVLAGGPRN HGLFVIRQSE TRPGEYVLTF NFQGKAKHLR LSLNGHGQCH
     VQHLWFQSVL DMLRHFHTHP IPLESGGSAD ITLRSYVRAQ GP
//
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