ID A0A0D9RZU8_CHLSB Unreviewed; 202 AA.
AC A0A0D9RZU8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Interleukin 17D {ECO:0000313|Ensembl:ENSCSAP00000014137.1};
GN Name=IL17D {ECO:0000313|Ensembl:ENSCSAP00000014137.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000014137.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000014137.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000014137.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
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DR EMBL; AQIB01113994; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9RZU8; -.
DR STRING; 60711.ENSCSAP00000014137; -.
DR Ensembl; ENSCSAT00000016216.1; ENSCSAP00000014137.1; ENSCSAG00000018119.1.
DR eggNOG; ENOG502RXIG; Eukaryota.
DR GeneTree; ENSGT00940000161739; -.
DR OMA; YDPKRYP; -.
DR Proteomes; UP000029965; Chromosome 3.
DR Bgee; ENSCSAG00000018119; Expressed in prefrontal cortex and 5 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR GO; GO:1903707; P:negative regulation of hemopoiesis; IEA:Ensembl.
DR GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IEA:Ensembl.
DR GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR GO; GO:0032757; P:positive regulation of interleukin-8 production; IEA:Ensembl.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..202
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012813821"
FT REGION 65..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 202 AA; 21832 MW; 1F495C3B3019EDCB CRC64;
MLVAGFLLAL PPGWAAGAPR AGRRPARPRG CADRPEELLE QLYGRLAAGV LSAFHHTLQL
GPREQARNAS CPAGGRPADR RFRPPTNLRS VSPWAYRISY DPARYPRYLP EAYCLCRGCL
TGLFGEEDVR FRSAPVYMPT VVLRRTPACA GGRSVYTEAY VTIPVGCTCV PEPEKDADSI
NSSIDKPGAK LLLGPNDAPA GP
//
