ID A0A0D9S1M7_CHLSB Unreviewed; 220 AA.
AC A0A0D9S1M7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=WAP four-disulfide core domain 1 {ECO:0000313|Ensembl:ENSCSAP00000014766.1};
GN Name=WFDC1 {ECO:0000313|Ensembl:ENSCSAP00000014766.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000014766.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000014766.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000014766.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01129883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007992412.1; XM_007994221.1.
DR AlphaFoldDB; A0A0D9S1M7; -.
DR STRING; 60711.ENSCSAP00000014766; -.
DR Ensembl; ENSCSAT00000001310.1; ENSCSAP00000014766.1; ENSCSAG00000003296.1.
DR KEGG; csab:103233392; -.
DR eggNOG; ENOG502QWDC; Eukaryota.
DR GeneTree; ENSGT00390000014299; -.
DR OMA; RFYKEYP; -.
DR OrthoDB; 2919884at2759; -.
DR BioGRID-ORCS; 103233392; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 5.
DR Bgee; ENSCSAG00000003296; Expressed in adrenal cortex and 6 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR GO; GO:0061045; P:negative regulation of wound healing; IEA:Ensembl.
DR Gene3D; 4.10.75.10; Elafin-like; 1.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR008197; WAP_dom.
DR InterPro; IPR042357; WFDC1.
DR PANTHER; PTHR14308; WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1; 1.
DR PANTHER; PTHR14308:SF0; WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1; 1.
DR Pfam; PF00095; WAP; 1.
DR SMART; SM00217; WAP; 1.
DR SUPFAM; SSF57256; Elafin-like; 1.
DR PROSITE; PS51390; WAP; 1.
PE 4: Predicted;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..220
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002346474"
FT DOMAIN 59..108
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT REGION 45..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 24059 MW; 1D0B75C3FF23D91F CRC64;
MPLTSVGPGS CRRQIIQALC LLLLLLHAGS AKNIWKRALP ARLAEKSRTE EAGAPGGSRQ
PRADRCPPPP RTMPPGACQA VRCQADSECP RHRRCCYNGC AYACLEAVPP PPVLDWLVQP
KPRWLGGNGW LLDGPEEVLQ AEACSTTEDG AEPLLCPSGY ECHILSPGDV AEGIPNRGQC
VKQRRQADGR ILRHKLYKEY PDGDSKNVAE PGRGQQRHFQ
//
