ID A0A0D9S205_CHLSB Unreviewed; 185 AA.
AC A0A0D9S205;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA replication complex GINS protein PSF2 {ECO:0000256|PIRNR:PIRNR028998};
GN Name=GINS2 {ECO:0000313|Ensembl:ENSCSAP00000014894.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000014894.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000014894.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000014894.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family.
CC {ECO:0000256|ARBA:ARBA00010565, ECO:0000256|PIRNR:PIRNR028998}.
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DR EMBL; AQIB01129918; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007992452.1; XM_007994261.1.
DR AlphaFoldDB; A0A0D9S205; -.
DR STRING; 60711.ENSCSAP00000014894; -.
DR Ensembl; ENSCSAT00000001176.1; ENSCSAP00000014894.1; ENSCSAG00000003148.1.
DR GeneID; 103233408; -.
DR KEGG; csab:103233408; -.
DR CTD; 51659; -.
DR eggNOG; KOG4071; Eukaryota.
DR GeneTree; ENSGT00390000007838; -.
DR OMA; DSLNCMY; -.
DR OrthoDB; 5487178at2759; -.
DR BioGRID-ORCS; 103233408; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 5.
DR Bgee; ENSCSAG00000003148; Expressed in fibroblast and 1 other cell type or tissue.
DR GO; GO:0071162; C:CMG complex; IEA:Ensembl.
DR GO; GO:0000811; C:GINS complex; IEA:Ensembl.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR CDD; cd11712; GINS_A_psf2; 1.
DR CDD; cd21694; GINS_B_Psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR028998};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR028998};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 42..153
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
SQ SEQUENCE 185 AA; 21402 MW; 57C918B1ED76F93C CRC64;
MDAAEVEFLA EKELVTIIPN FSLDKIYLIG GDLGPFNPGL PVEVPLWLAI NLKQRQKCRL
LPPEWMDVEK LEKMRDHERK EETFTPMPSP YYMELTKLLL NHASDNIPKA DEIRTLVKDM
WDTRIAKLRV SADSFVRQQE AHAKLDNLTL MEINTSGTFL TQALNHMYKL RTNLQPSEST
QSQDF
//
