ID A0A0D9S2M4_CHLSB Unreviewed; 184 AA.
AC A0A0D9S2M4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Adrenal ferredoxin {ECO:0000256|ARBA:ARBA00042934};
DE AltName: Full=Ferredoxin-1 {ECO:0000256|ARBA:ARBA00041333};
GN Name=FDX1 {ECO:0000313|Ensembl:ENSCSAP00000015113.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000015113.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000015113.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000015113.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- SUBUNIT: Interacts with CYP11A1. {ECO:0000256|ARBA:ARBA00038759}.
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DR EMBL; AQIB01092646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01092647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01092648; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008018974.1; XM_008020783.1.
DR AlphaFoldDB; A0A0D9S2M4; -.
DR STRING; 60711.ENSCSAP00000015113; -.
DR Ensembl; ENSCSAT00000000950.1; ENSCSAP00000015113.1; ENSCSAG00000002924.1.
DR GeneID; 103248424; -.
DR KEGG; csab:103248424; -.
DR CTD; 2230; -.
DR eggNOG; KOG3309; Eukaryota.
DR GeneTree; ENSGT00940000156916; -.
DR OMA; TPMEEDM; -.
DR OrthoDB; 36668at2759; -.
DR BioGRID-ORCS; 103248424; 3 hits in 16 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 1.
DR Bgee; ENSCSAG00000002924; Expressed in adrenal cortex and 7 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:Ensembl.
DR GO; GO:0009055; F:electron transfer activity; IEA:Ensembl.
DR GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR GO; GO:1904322; P:cellular response to forskolin; IEA:Ensembl.
DR GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0042446; P:hormone biosynthetic process; IEA:Ensembl.
DR GO; GO:0140647; P:P450-containing electron transport chain; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR001055; Adrenodoxin.
DR InterPro; IPR018298; Adrenodoxin_Fe-S_BS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR PANTHER; PTHR23426:SF26; ADRENODOXIN, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23426; FERREDOXIN/ADRENODOXIN; 1.
DR Pfam; PF00111; Fer2; 1.
DR PRINTS; PR00355; ADRENODOXIN.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00814; ADX; 1.
PE 4: Predicted;
KW Cholesterol metabolism {ECO:0000256|ARBA:ARBA00022548};
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Steroidogenesis {ECO:0000256|ARBA:ARBA00023250};
KW Sterol metabolism {ECO:0000256|ARBA:ARBA00023166}.
FT DOMAIN 67..171
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 184 AA; 19394 MW; DF90F6E2CDB34329 CRC64;
MAAAGGARLL RAASAVLGGP CGWWLHHAGS RAGVSGLLRS WGPGGSAGAS RPLSVSARAR
SSSEDKITVH FINRDGETLT TKGKVGDSLL DVVVENNLDI DGFGACEGTL ACSTCHLIFE
DHIYEKLDAI TDEENDMLDL AYGLTDRSRL GCQICLTKSM DNMTVRVPET VADARQSVDV
GKTS
//
