ID A0A0D9S402_CHLSB Unreviewed; 257 AA.
AC A0A0D9S402;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Fc epsilon receptor Ia {ECO:0000313|Ensembl:ENSCSAP00000015591.1};
GN Name=FCER1A {ECO:0000313|Ensembl:ENSCSAP00000015591.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000015591.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000015591.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000015591.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01138736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9S402; -.
DR STRING; 60711.ENSCSAP00000015591; -.
DR Ensembl; ENSCSAT00000000467.1; ENSCSAP00000015591.1; ENSCSAG00000002450.1.
DR eggNOG; ENOG502RTXR; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR OMA; IRCHSWK; -.
DR Proteomes; UP000029965; Chromosome 20.
DR Bgee; ENSCSAG00000002450; Expressed in blood and 3 other cell types or tissues.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019768; F:high-affinity IgE receptor activity; IEA:Ensembl.
DR GO; GO:0019863; F:IgE binding; IEA:Ensembl.
DR GO; GO:0043308; P:eosinophil degranulation; IEA:Ensembl.
DR GO; GO:0043303; P:mast cell degranulation; IEA:Ensembl.
DR GO; GO:0042092; P:type 2 immune response; IEA:Ensembl.
DR GO; GO:0016068; P:type I hypersensitivity; IEA:Ensembl.
DR CDD; cd05752; Ig1_FcgammaR_like; 1.
DR CDD; cd05753; Ig2_FcgammaR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11481:SF12; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..257
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002346688"
FT TRANSMEM 202..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..110
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 122..193
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 257 AA; 29401 MW; 52852F046E182BEA CRC64;
MAPAMESPTL LCVALLFFAP DGMLAVPQKP TVSLNPPWNR IFKGENVTLT CNGSNFAEVS
SMKWFHNGSL SEVANSSLNI VNADFEDSGE YKCQHQQFDD SEPVHLEVFS DWLLLQASAE
VVMEGQPLFL RCHSWRNWDV YKVIYYKDGE ALKYWYENHN ISITNATVED SGIYYCTGKL
WQLDYESEPL NITVIKAQHD KYWLQFLIPL LVAILFAVDT GLFISTQQQV TFLLKIKRTR
KGFKLLNPHP KPNPKSN
//
