ID   A0A0D9S4Q9_CHLSB        Unreviewed;       475 AA.
AC   A0A0D9S4Q9;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Methyltransferase like 25B {ECO:0000313|Ensembl:ENSCSAP00000015848.1};
GN   Name=METTL25B {ECO:0000313|Ensembl:ENSCSAP00000015848.1};
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000015848.1, ECO:0000313|Proteomes:UP000029965};
RN   [1] {ECO:0000313|Ensembl:ENSCSAP00000015848.1, ECO:0000313|Proteomes:UP000029965}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAP00000015848.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AQIB01138792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_007974911.1; XM_007976720.1.
DR   AlphaFoldDB; A0A0D9S4Q9; -.
DR   STRING; 60711.ENSCSAP00000015848; -.
DR   Ensembl; ENSCSAT00000000205.1; ENSCSAP00000015848.1; ENSCSAG00000002189.1.
DR   GeneID; 103223827; -.
DR   KEGG; csab:103223827; -.
DR   CTD; 51093; -.
DR   eggNOG; KOG2651; Eukaryota.
DR   GeneTree; ENSGT00530000063745; -.
DR   OMA; QQARKWD; -.
DR   OrthoDB; 3060170at2759; -.
DR   BioGRID-ORCS; 103223827; 0 hits in 9 CRISPR screens.
DR   Proteomes; UP000029965; Chromosome 20.
DR   Bgee; ENSCSAG00000002189; Expressed in adrenal cortex and 7 other cell types or tissues.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12496:SF2; METHYLTRANSFERASE-LIKE PROTEIN 25B; 1.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS01131; RRNA_A_DIMETH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT   DOMAIN          133..291
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13679"
SQ   SEQUENCE   475 AA;  53022 MW;  A713CCABE4730CF5 CRC64;
     MPGISARGLS HEGRRQLAVN LTRVLALYRS ILDAYIIEFF TDNLWDTLPC SWQEALDGLN
     PPQLATMLLG MPGEGEVIRY RSVWPLTLLA LKSTACALAF TRTPGFQTPS EFLENPSQSS
     RLTAPFRKHV RPKKQHEIRR LGELVKKLSD FTGCTQVVDV GSGQGHLSRF MALGLGLMVK
     SIEGDQRLVE RAQRLDQELL QALEKEEKRN PQVVQTSPRH SPHHVVRWVD PTALCEELLL
     PLENPCQGRA RLLLTGLHAC GDLSVALLRH FSCCPEVVAL ASVGCCYMKL SDPGGYPLSQ
     WVAGLPGYEL PYRLREGACH ALEEYAERLQ KAGPGLRTHC YRAALETVIR RARPELRRPG
     VQGIPRVHEL KIEEYVQRGL QRVGLDPQLP LNLAALQAHQ AQENRVVAFF SLALLLAPLV
     ETLILLDRLL YLQEQGFHAE LLPIFSPELS PRNLVLVATK MPLGQALSIL ETEDS
//