ID A0A0D9S6U2_CHLSB Unreviewed; 298 AA.
AC A0A0D9S6U2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Heparan sulfate 2-O-sulfotransferase 1 {ECO:0000256|ARBA:ARBA00039773};
GN Name=HS2ST1 {ECO:0000313|Ensembl:ENSCSAP00000016581.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000016581.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000016581.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000016581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010569}.
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DR EMBL; AQIB01085685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01085686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9S6U2; -.
DR STRING; 60711.ENSCSAP00000016581; -.
DR Ensembl; ENSCSAT00000017092.1; ENSCSAP00000016581.1; ENSCSAG00000001441.1.
DR eggNOG; KOG3922; Eukaryota.
DR GeneTree; ENSGT00530000063408; -.
DR OMA; NITANMH; -.
DR Proteomes; UP000029965; Chromosome 20.
DR Bgee; ENSCSAG00000001441; Expressed in caudate nucleus and 7 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004394; F:heparan sulfate 2-O-sulfotransferase activity; IEA:Ensembl.
DR GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR GO; GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IEA:Ensembl.
DR GO; GO:0030202; P:heparin metabolic process; IEA:Ensembl.
DR GO; GO:0060676; P:ureteric bud formation; IEA:Ensembl.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12129:SF17; HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
SQ SEQUENCE 298 AA; 35101 MW; E8EE1715EBE080FA CRC64;
MDGPRQDATL DEEEDMVIIY NRVPKTASTS FTNIAYDLCA KNKYHVLHIN TTKNNPVMSL
QDQVRFVKNI TSWKEMKPGF YHGHVSYLDF AKFGVKKKPI YINVIRDPIE RLVSYYYFLR
FGDDYRPGLR RRKQGDKKTF DECVAEGGSD CAPEKLWLQI PFFCGHSSEC WNVGSRWAMD
QAKYNLVNEY FLVGVTEELE DFIMLLEAAL PRFFRGATEL YRTGKKSHLR KTTEKKLPTK
QTIAKLQQSD IWKMENEFYE FALEQFQFIR AHAVREKDGD LYILAQNFFY EKIYPKSN
//
