ID A0A0D9SB54_CHLSB Unreviewed; 438 AA.
AC A0A0D9SB54;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Solute carrier family 10 member 5 {ECO:0000313|Ensembl:ENSCSAP00000018093.1};
GN Name=SLC10A5 {ECO:0000313|Ensembl:ENSCSAP00000018093.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000018093.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000018093.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000018093.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC 2.A.28) family. {ECO:0000256|ARBA:ARBA00006528}.
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DR EMBL; AQIB01087604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9SB54; -.
DR STRING; 60711.ENSCSAP00000018093; -.
DR Ensembl; ENSCSAT00000018646.1; ENSCSAP00000018093.1; ENSCSAG00000018556.1.
DR eggNOG; KOG2718; Eukaryota.
DR GeneTree; ENSGT00950000182808; -.
DR OMA; KHRIPEK; -.
DR Proteomes; UP000029965; Chromosome 8.
DR Bgee; ENSCSAG00000018556; Expressed in liver.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR004710; Bilac:Na_transpt.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR PANTHER; PTHR10361:SF29; SODIUM_BILE ACID COTRANSPORTER 5; 1.
DR Pfam; PF01758; SBF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Signal {ECO:0000256|SAM:SignalP}; Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022847}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..438
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002346627"
FT TRANSMEM 176..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 438 AA; 48904 MW; 4ABE202B187BC30A CRC64;
MIRKLFIVLL LLLVTVEAAR MSSLSFLNIE KMEILFFTKT EETIIVSSRY EDKQPNFSHL
FVKIEDPKIL QMVNVTKKIS SDATNFAINL VTDEEGETNV TIQLWDSEGR QERLIEEIKN
VKVKVLKRKD SLLQASMPID RNILMLILPL ILLNKCAFGC KIELQVFQTV WKRPLPVILG
AVTQFFLLPF CGFLLSQIVA LPEAQAFGVV MTCTCPGGGG GYLFALLLDG DFTLAILMTC
TSTFLALIMM PVNSYIYSKI LGLSGTFHIP VSKIVSTLLF ILVPVSVGIV IKRRIPEKAS
FLERIIRPLS FILMFVGIYL TFTVGLMFLK TDNLEVILLG LLVPALGLLF GYSFAKVCML
PLPVCKTVAI ESGMLNSFLA LAIIQLSFPQ SKANLASVAP FTVAMCSGCE MLLIILVYKA
KKRCIFFLQD KRKRNSLI
//
