ID A0A0D9SE53_CHLSB Unreviewed; 521 AA.
AC A0A0D9SE53;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Nucleoporin 62 {ECO:0000313|Ensembl:ENSCSAP00000019142.1};
GN Name=NUP62 {ECO:0000313|Ensembl:ENSCSAP00000019142.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000019142.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000019142.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000019142.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nucleoporin NSP1/NUP62 family.
CC {ECO:0000256|ARBA:ARBA00005911}.
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DR EMBL; AQIB01135570; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007995812.1; XM_007997621.1.
DR RefSeq; XP_007995813.1; XM_007997622.1.
DR AlphaFoldDB; A0A0D9SE53; -.
DR STRING; 60711.ENSCSAP00000019142; -.
DR Ensembl; ENSCSAT00000019736.1; ENSCSAP00000019142.1; ENSCSAG00000019646.1.
DR GeneID; 103235065; -.
DR KEGG; csab:103235065; -.
DR CTD; 23636; -.
DR eggNOG; KOG2196; Eukaryota.
DR GeneTree; ENSGT00940000161737; -.
DR OMA; EMMSKQV; -.
DR OrthoDB; 11989at2759; -.
DR BioGRID-ORCS; 103235065; 2 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 6.
DR Bgee; ENSCSAG00000019646; Expressed in adrenal cortex and 7 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0090543; C:Flemming body; IEA:Ensembl.
DR GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0030544; F:Hsp70 protein binding; IEA:Ensembl.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:Ensembl.
DR GO; GO:0051425; F:PTB domain binding; IEA:Ensembl.
DR GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
DR GO; GO:0030159; F:signaling receptor complex adaptor activity; IEA:Ensembl.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:Ensembl.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0090398; P:cellular senescence; IEA:Ensembl.
DR GO; GO:0098534; P:centriole assembly; IEA:Ensembl.
DR GO; GO:0007100; P:mitotic centrosome separation; IEA:Ensembl.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:Ensembl.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0046601; P:positive regulation of centriole replication; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:1903438; P:positive regulation of mitotic cytokinetic process; IEA:Ensembl.
DR GO; GO:0045840; P:positive regulation of mitotic nuclear division; IEA:Ensembl.
DR GO; GO:1904781; P:positive regulation of protein localization to centrosome; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0060236; P:regulation of mitotic spindle organization; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR026010; NSP1/NUP62.
DR InterPro; IPR007758; Nucleoporin_NSP1_C.
DR PANTHER; PTHR12084:SF0; NUCLEAR PORE GLYCOPROTEIN P62; 1.
DR PANTHER; PTHR12084; NUCLEAR PORE GLYCOPROTEIN P62-RELATED; 1.
DR Pfam; PF05064; Nsp1_C; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 323..428
FT /note="Nucleoporin NSP1-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05064"
FT REGION 171..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 329..391
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 171..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 52852 MW; 623DF44AAAA93AB0 CRC64;
MSGFNFGGTG APTGGFTFGT AKTATTTPAT GFSFSTSGTG GFNFGAPSQP TTSTPSTGLF
SLATQTPATQ TTGFTFGTAT LASGGTGFSL GIGASKLNLS NTAATPAMAN PSGFGLGSSN
LTNAISSTVT SSQGTAPTGF VFGPSTTSVA PATTSGGFSF TGGSTAQPSG FSIGSAGNSA
QPTAPAALPF TPATPAATTT GVTQPAAPTA TATTTGTGPT LFASIATAPT SSATTGLSLC
TPATTAGAPA AGTQGFSLKA PGAASGASTT TSTAAAAATS SSSSSSTGFA LNLKPLAPAG
IPSNTAAAVT APPGPGAAAG AAASSAMTYA QLESLINKWS LELEDQERHF LQQATQVNAW
DRTLIENGEK ITSLHREVEK VKLDQKRLDQ ELDFILSQQK ELEDLLSPLE ELVKEQSGTI
YLQHADEERE KTYKLAENID AQLKRMAQDL KDIIEHLNTS GAPADTSDPL QQICKILNAH
MGSLQWIDQN SALLQRKVEE VTKVCEGRRK EQERSFRITF D
//
