ID   A0A0D9VLJ5_9ORYZ        Unreviewed;       973 AA.
AC   A0A0D9VLJ5;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=separase {ECO:0000256|ARBA:ARBA00012489};
DE            EC=3.4.22.49 {ECO:0000256|ARBA:ARBA00012489};
OS   Leersia perrieri.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Leersia.
OX   NCBI_TaxID=77586 {ECO:0000313|EnsemblPlants:LPERR02G27920.1, ECO:0000313|Proteomes:UP000032180};
RN   [1] {ECO:0000313|EnsemblPlants:LPERR02G27920.1, ECO:0000313|Proteomes:UP000032180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wing R.A.;
RT   "Oryza genome evolution.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:LPERR02G27920.1, ECO:0000313|Proteomes:UP000032180}
RP   NUCLEOTIDE SEQUENCE.
RA   Yu Y., Lee S., de Baynast K., Wissotski M., Liu L., Talag J.,
RA   Goicoechea J., Angelova A., Jetty R., Kudrna D., Golser W., Rivera L.,
RA   Zhang J., Wing R.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:LPERR02G27920.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=All bonds known to be hydrolyzed by this endopeptidase have
CC         arginine in P1 and an acidic residue in P4. P6 is often occupied by
CC         an acidic residue or by a hydroxy-amino-acid residue, the
CC         phosphorylation of which enhances cleavage.; EC=3.4.22.49;
CC         Evidence={ECO:0000256|ARBA:ARBA00000451};
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DR   AlphaFoldDB; A0A0D9VLJ5; -.
DR   STRING; 77586.A0A0D9VLJ5; -.
DR   EnsemblPlants; LPERR02G27920.1; LPERR02G27920.1; LPERR02G27920.
DR   Gramene; LPERR02G27920.1; LPERR02G27920.1; LPERR02G27920.
DR   eggNOG; KOG1849; Eukaryota.
DR   Proteomes; UP000032180; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0098813; P:nuclear chromosome segregation; IEA:UniProt.
DR   GO; GO:0000280; P:nuclear division; IEA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR005314; Peptidase_C50.
DR   InterPro; IPR030397; SEPARIN_core_dom.
DR   PANTHER; PTHR12792; EXTRA SPINDLE POLES 1-RELATED; 1.
DR   PANTHER; PTHR12792:SF0; SEPARIN; 1.
DR   Pfam; PF03568; Peptidase_C50; 1.
DR   PROSITE; PS51700; SEPARIN; 1.
PE   4: Predicted;
KW   Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032180}.
FT   DOMAIN          745..839
FT                   /note="Peptidase C50"
FT                   /evidence="ECO:0000259|PROSITE:PS51700"
FT   REGION          88..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          909..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        909..928
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   973 AA;  109346 MW;  BF468AC43FD1E908 CRC64;
     MYQSALDKLN NKLEFPVGLY DKLKTTCIAC NHVKESLAAI DGVLPSCAVC ANFSQASGDH
     SNEFMAVKSQ KHKDSEGCPP LDVKAKRTTR NSSRLAKEQH VEAHAKTKTR SSKRTGHVKG
     EKASTELNCK NDISCSDYLS TNDLARGKAS CFIGGVDQRI DYTCDTFGCW NCLFVNSLNS
     GSIQNILQFR WDCVWHHNHV SILLKIARVL GAHGGLHGAH KVHNIYWQCI SSLYFRSLPQ
     DYYKTYEHDL FGLIMDENTG DFVNSERAEI LYSMSLFLLK GFLSEQSRAV CCRFCSIQMS
     DVVPWLLKAF VLSRENPSIF QEVCRLLACI FLLATIDSTT QLPLYSNGSL SLNHWAAYFH
     QNSVGTYLDC HYFASLESPP RKKYSKVSVE NFTNESDNGL SMFLRFSSAD IGQLEIHIKE
     FFHKLPDVPI VCISMLEGDF VNVLGEILLL PSYFPAWMLL SRFDSKTKPI TMLLPVDAIL
     EETQHEEASI DELDNQVRAS DKNWLCPWGY TIIDYVAPTF RKILEKNFIS LSSATLTLND
     GQANHVRWWS QRTKLNNHLD KILKNIEESW LGPWKCLLLG YHLTDQHIEE VLTNLIDGLE
     SDFKFEVNPA LIKVILGGAT SVDEVHDCVS QLITYKGYFG RGGCCGKDRL RAFSSCCIES
     EALEAVECLV KSTVNELTEP VDRDPVIFVL DINVQMLPWE NLPVLRNQEI YRMPSMGSIF
     LALTRSNNYG KDACVIAPPF PVIDPFNTFY LLNPSGDLSS TQEEFDRLFK NYEWKGKAGH
     APSAEELVLA LRNHDLFLYF GHGSGTQYVS GKEIEKLDNC AAALLMGCSS GTLHCKGGYA
     PQGAPLSYLS AGSPAVIANL WDVSDKDIDR FSKALLNSWL QENFVAAKNC SKCCQLTQDF
     ESMTIAVEDN NRPRRRGTRR KKSEETNNSS KRCTCGNRRI ASYLSEARRA CRLPLMIGGS
     PVCYGVPTII RKK
//