ID A0A0D9WTH2_9ORYZ Unreviewed; 1101 AA.
AC A0A0D9WTH2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399, ECO:0000256|PIRNR:PIRNR036573};
DE EC=2.7.7.- {ECO:0000256|PIRNR:PIRNR036573};
OS Leersia perrieri.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Leersia.
OX NCBI_TaxID=77586 {ECO:0000313|EnsemblPlants:LPERR06G21230.2, ECO:0000313|Proteomes:UP000032180};
RN [1] {ECO:0000313|EnsemblPlants:LPERR06G21230.2, ECO:0000313|Proteomes:UP000032180}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.A.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:LPERR06G21230.2, ECO:0000313|Proteomes:UP000032180}
RP NUCLEOTIDE SEQUENCE.
RA Yu Y., Lee S., de Baynast K., Wissotski M., Liu L., Talag J.,
RA Goicoechea J., Angelova A., Jetty R., Kudrna D., Golser W., Rivera L.,
RA Zhang J., Wing R.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:LPERR06G21230.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a
CC dCMP residue from dCTP to the 3'-end of a DNA primer in a template-
CC dependent reaction. May assist in the first step in the bypass of
CC abasic lesions by the insertion of a nucleotide opposite the lesion.
CC Required for normal induction of mutations by physical and chemical
CC agents. {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945, ECO:0000256|PIRNR:PIRNR036573}.
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DR AlphaFoldDB; A0A0D9WTH2; -.
DR EnsemblPlants; LPERR06G21230.2; LPERR06G21230.2; LPERR06G21230.
DR Gramene; LPERR06G21230.2; LPERR06G21230.2; LPERR06G21230.
DR HOGENOM; CLU_003901_0_0_1; -.
DR Proteomes; UP000032180; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR PIRSF; PIRSF036573; REV1; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR036573};
KW DNA repair {ECO:0000256|PIRNR:PIRNR036573};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634,
KW ECO:0000256|PIRNR:PIRNR036573};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036573};
KW Reference proteome {ECO:0000313|Proteomes:UP000032180};
KW Transferase {ECO:0000256|PIRNR:PIRNR036573}.
FT DOMAIN 86..170
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 382..561
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1101 AA; 120546 MW; 08E5D7238F182BC5 CRC64;
MSASSSGRHG GGAPPPPAAS PGQKRPRGDD PSSPSNRSSD SAAPAKNPRR AFSSSPFADF
GSYMATKNSK LAAQFEADAS TSAAEASGGV FAGVSIFVDG FTVPSSQELK EIMLNNGGRF
VNYFSRNTVT HIICTHLPNS KMNNLRAFSR GLPVVKPAWV VDSLAENRLL SCSVPYQISQ
HSSSSQKQTK LSTFFSGRHC QGGLNDQNKG HELQSSSAQE GSQDQNSGCE KEGSLLKEEA
SKDSLSSDDH KASMLEEQDS DDFVDEDGNA CETACSERRD NDVDGELDVA ESPGIRSRCS
NLCSTSSTGS HLSLDSLDKN ATKSSIRTHS TLTDANFVEN YFKYSRLHFI GTWRNRYRKR
FSNLLGAKSS KGNSDHSGNK TIIHIDMDCF FVSVVIRNMP ELHDKPVAVC HSDNPKGTAE
ISSANYPARN YGIKAGMFVR DAKARCPHLM IVPYDFDAYG EVADQFYGIL HKYCSKVQAL
SCDEAFLDMT ECLHDNPEEV TQKIRNEIFS TTKCSASIAG NMLLARLATR SAKPNGQCFI
SSEKVDDYLN TLSIKALPGI GHAVSDKLKD KEIEFCGQLR NIPKEILHKD FGKKIGDMLW
NYCRGIDHSV VEAVQETKSV GAEVNWGVRF NDNKDAENFL ANLSKEVCLR LQGCGVQGRT
ITLKVKTRRK GAGEPIKFMG CGDCETVSRS MTIAGATDNL VTLQRITKQL FVSLRVDVKE
VRGVGLKISR LEHADLARGA PQGNMLESWL VSPSEKLKKH TSEKACLFKS GDDAETSKRR
GLGSIRPSCV GETSRSSEVN LTIGRSTIVH GVELPPLSEL DLEVLKNLPP EIISEMNDMY
KGELHGFLGI TSGAKAKESD IKPIDFPAVT ENIVPGSSVK KLSEVKDANA SFLRASELVD
IATESVIQHD FMPTSLSQAD FAVLQELPED VKADLFNVLP LHRSGDPTCS TSDISENKFP
EDGRSNDPKH PQTCVLPGNS QKWIEEFRVS SCVILNVLAE KHTDSISGQP LSSVLEPLVS
YLHLCPNSGS EEWNEALACL SELLTQYIHL KVESDIEELY KCFRLLKRLS SASEFFLELH
DSILPLLQDS VSQHYGGILH F
//
