ID A0A0D9XSJ2_9ORYZ Unreviewed; 1000 AA.
AC A0A0D9XSJ2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
OS Leersia perrieri.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Leersia.
OX NCBI_TaxID=77586 {ECO:0000313|EnsemblPlants:LPERR11G12030.3, ECO:0000313|Proteomes:UP000032180};
RN [1] {ECO:0000313|EnsemblPlants:LPERR11G12030.3, ECO:0000313|Proteomes:UP000032180}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.A.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:LPERR11G12030.3, ECO:0000313|Proteomes:UP000032180}
RP NUCLEOTIDE SEQUENCE.
RA Yu Y., Lee S., de Baynast K., Wissotski M., Liu L., Talag J.,
RA Goicoechea J., Angelova A., Jetty R., Kudrna D., Golser W., Rivera L.,
RA Zhang J., Wing R.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:LPERR11G12030.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361199};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR AlphaFoldDB; A0A0D9XSJ2; -.
DR STRING; 77586.A0A0D9XSJ2; -.
DR EnsemblPlants; LPERR11G12030.1; LPERR11G12030.1; LPERR11G12030.
DR EnsemblPlants; LPERR11G12030.3; LPERR11G12030.3; LPERR11G12030.
DR Gramene; LPERR11G12030.1; LPERR11G12030.1; LPERR11G12030.
DR Gramene; LPERR11G12030.3; LPERR11G12030.3; LPERR11G12030.
DR eggNOG; KOG1959; Eukaryota.
DR HOGENOM; CLU_004690_2_0_1; -.
DR Proteomes; UP000032180; Chromosome 11.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR CDD; cd10810; GH38N_AMII_LAM_like; 1.
DR Gene3D; 2.60.40.1360; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR048534; Man2a1-like_dom.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR Pfam; PF21260; Laman-like_dom; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW Hydrolase {ECO:0000256|RuleBase:RU361199};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361199};
KW Reference proteome {ECO:0000313|Proteomes:UP000032180};
KW Signal {ECO:0000256|RuleBase:RU361199};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT CHAIN 22..1000
FT /note="Alpha-mannosidase"
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT /id="PRO_5007398530"
FT DOMAIN 355..429
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1000 AA; 112278 MW; 03E8D0570E05C00A CRC64;
MGAAVRLAVL LLVAAAAVVE AVYIPYNTSA GVVKGKLNVH VVPHTHDDVG WLKTVDQYYV
GSNNSIQGAC VQNVLDSLVP ALLKDENRKF IYVEQAFFQR WWRQQNDMIK DIVKGLISTG
RLELINGGMC MHDEATVHYI DMIDQTTLGH RFIKEEFGQI PRIGWQIDPF GHSAVQAYLL
GTEVGFDAFY FFRIDYQDRD TRKGTKELEV VWRGSKTFGS SADIFAGIFP KNYEPPPGEF
YFEVDDTSPL VQDDPLLFDY NVQQRVNDFV DAALAQANIT RTNHVMFTMG TDFKYQYAES
WFRQMDKLIH YVNKDGRVNA LYSTPSIYTD AKHAENEKWP LKTNDFFPYA DDPNAYWTGY
FTSRPALKRY VRVMSGYYLA ARQLEFFKGR SNSDHRTDSL GDALALAQHH DAVTGTEKQH
VANDYAKRLA IGYTQAEKLV SSSLSCLSQS GSKSHCLSQT TNFGQCPLLN ITYCPPSETN
LSQGKSLVVL VYNSLGWKRE DVLRIPVLSD SIVVHDSEGR EVESQLLPIA NASLHMREKH
VKAYLGMLPA AKPKFWLAFP VSVPPLGFNT YFISSGKKSA SLSLMSTLHP SQGSENSNTQ
IGQGHLKLQY NAAGKLSLYS NSKSQVEANF EQKYKYYIGQ DGNGSDPQAS GAYIFRPNGT
VPIKTNGQVP LTVLRGPILD EVHQQINSWI YQINRIYKGK DYVETEFIVG PIPVDDGNGK
EVSTEIVTNM ATNKTFYTDS SGRDFIKRIR DYRSEWKIEV HQPIAGNYYP VNLGIYVEDG
SRELSILVDR SVGGASIKDG QIELMLHRRL LHDDGRGVAE ALNETTCFDN QCEGLVIEGK
YYLKIDPQGE GSRWRRTFGQ EIYSPLLLAF AEQDGGNWVN SHVTKFSAMD PTYSLPDNVA
LLTLQAGEHK ELSALASVDL KRVFPDKKIG KIVETSLSAN QERSAMEKKR LKWKVEGPPA
DEKIVRGGPI DPSKLIVELG PMEIRTFLVN FSQQSGKQLM
//
