ID A0A0D9YTJ2_9ORYZ Unreviewed; 361 AA.
AC A0A0D9YTJ2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|ARBA:ARBA00012720};
DE EC=4.2.99.18 {ECO:0000256|ARBA:ARBA00012720};
OS Oryza glumipatula.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=40148 {ECO:0000313|EnsemblPlants:OGLUM02G20560.1};
RN [1] {ECO:0000313|EnsemblPlants:OGLUM02G20560.1}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.A., Panaud O., Oliveira A.C.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OGLUM02G20560.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-
CC deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-
CC dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-
CC 2'-deoxyribonucleoside-DNA + H(+); Xref=Rhea:RHEA:66592, Rhea:RHEA-
CC COMP:13180, Rhea:RHEA-COMP:16897, Rhea:RHEA-COMP:17067,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:136412, ChEBI:CHEBI:157695,
CC ChEBI:CHEBI:167181; EC=4.2.99.18;
CC Evidence={ECO:0000256|ARBA:ARBA00024490};
CC -!- SIMILARITY: Belongs to the type-1 OGG1 family.
CC {ECO:0000256|ARBA:ARBA00010679}.
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DR AlphaFoldDB; A0A0D9YTJ2; -.
DR STRING; 40148.A0A0D9YTJ2; -.
DR EnsemblPlants; OGLUM02G20560.1; OGLUM02G20560.1; OGLUM02G20560.
DR Gramene; OGLUM02G20560.1; OGLUM02G20560.1; OGLUM02G20560.
DR eggNOG; KOG2875; Eukaryota.
DR HOGENOM; CLU_027543_3_1_1; -.
DR Proteomes; UP000026961; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0008534; F:oxidized purine nucleobase lesion DNA N-glycosylase activity; IEA:EnsemblPlants.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.310.40; -; 1.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR012904; OGG_N.
DR PANTHER; PTHR10242; 8-OXOGUANINE DNA GLYCOSYLASE; 1.
DR PANTHER; PTHR10242:SF2; N-GLYCOSYLASE_DNA LYASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR Pfam; PF07934; OGG_N; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
DR SUPFAM; SSF55945; TATA-box binding protein-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000026961}.
FT DOMAIN 70..191
FT /note="8-oxoguanine DNA glycosylase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07934"
FT DOMAIN 195..302
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|Pfam:PF00730"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..35
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 39002 MW; E971C0002AC2706B CRC64;
MPPRRRRRVR PPLPPSPPLL SSTTATPPPT PPVGTPKSEA ADRRPPTARR RLPLVSAAAV
EEEDGEWHPL PLSAADLSLP LTLPTGQTFL WRRTSLSPLR FTGAVGPHLV SLSHLPSSDG
RLAFLLHNNG GSSSSSVPAA ARAALSDYLN AAVPLADLWR RFAAADARFA EVSARLGGGG
ARVLRQDPVE CVFQFLCSSN NNIARIEKMV WALAGYGERL GEVGGYQFHQ FPTIERLARV
SEQELRDAGF GYRAKYIVGT AKILQAKPGG GEKWLASLRT RELPEVATQY LMPELAGKSL
TPKLSVAVAD AFVAKFGNYA GWAQNVLFIG QLSAQKLMVA ETTNTSTKPT KRKRSGNNVK
T
//
