ID   A0A0E0A7H5_9ORYZ        Unreviewed;      1173 AA.
AC   A0A0E0A7H5;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE            EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
OS   Oryza glumipatula.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=40148 {ECO:0000313|EnsemblPlants:OGLUM06G09820.1};
RN   [1] {ECO:0000313|EnsemblPlants:OGLUM06G09820.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wing R.A., Panaud O., Oliveira A.C.;
RT   "Oryza genome evolution.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:OGLUM06G09820.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361199};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR   AlphaFoldDB; A0A0E0A7H5; -.
DR   STRING; 40148.A0A0E0A7H5; -.
DR   EnsemblPlants; OGLUM06G09820.1; OGLUM06G09820.1; OGLUM06G09820.
DR   Gramene; OGLUM06G09820.1; OGLUM06G09820.1; OGLUM06G09820.
DR   eggNOG; KOG1958; Eukaryota.
DR   HOGENOM; CLU_004690_1_0_1; -.
DR   Proteomes; UP000026961; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblPlants.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:EnsemblPlants.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:EnsemblPlants.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IEA:EnsemblPlants.
DR   CDD; cd10809; GH38N_AMII_GMII_SfManIII_like; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR   PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW   Hydrolase {ECO:0000256|RuleBase:RU361199};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361199};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026961};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT   TRANSMEM        59..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          500..585
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1173 AA;  133059 MW;  5A181AED4E8673A6 CRC64;
     MPFFSGGGGG RSGALLPTTS KPKGHHHLRS KGLSSPAASR RRGAHSASSS ASSSSRRRVL
     YVAAAAFAAL FLLAFFRLGL PSSRPAATSP ARLRPRLTRR PAFRRDSAAA EAAAAAVAAR
     IGREAHVDIT TKDLYDRIQF LDVDGGAWKQ GWEVSYKGDE WDGEKLKVFV APHSHNDPGW
     RLTVEEYYEK QSRHILDTII ESLSKDSRRK FLWEEMSYLE RWWRDAPRKK QEAFTKLVRD
     GQLEIVSGGW VMNDEMMEGN MWLNDTIGVV PKNSWSIDPF GYSATMAYLL RRMGFHNMLI
     QRTHYELKKE LAMNKNLEYL WRQNWDIDET TDIFVHMMPF YSYDIPHTCG PEPAICCQFD
     FARMRSFSYE SCPWRFDPVE TNANNVQERA MKLLDQYRKK STLYRTNTLL IPLGDDFRYV
     STEEAEAQFR NYEKLFDYIN SNPHLKAEVK FGTLEDYFST LRDEAERINY TRPGELVSSE
     LPGFPTLSGD FFTYADRNQD YWSGYYVSRP YFKAVDRVLE QTLRASEILS SFVLGYCQKL
     QCVKLPISFS HKLTAARRNL ALFQHHDGVT GTAKDHVVVD YGTRMHTSLQ DLQLFMSRAV
     EVLLGDIHDR SDPTLLSHFE PVQERSKYDV QPVYKVLNPH GGKAHSVVLF NPLEQTRDEI
     VMVVVSNPDV SVLNSNGSCL RSQISPEWQY VSGEKVSTGQ HRLYWRASVP ALGLETYYVA
     TGYDDCAKAT PAVVKAFTTA GQFPCPEPYV CSKLEGKTVE MKNSYHSLSF DVRHGLLQTV
     TRNKDGEHTD VGEEIGMYRS HGSGAYLFKP IGEAQSIVEE GGYFILSEGP LVQEAHSLPK
     TQWHKSPISH STRIYSCGDS IQDMLIEKEY HVELVGHVFN DKELIVKFKT DIDNQGVFYS
     DLNGFQMSRR QTYDKIPLQG NYYPMPSLAF LQDSLGNRFS VHSKQSLGAA SLKNGWLEIM
     LDRRLTQDDG RGLGQGVVDN RPMNVIFHLL RESNVSALPK THSLLTLQPS LLSHRVGAHL
     NYPMHAFVSK KAQEKSFRLA QQTFAPLTSP LPCDVHVVNL KAPQPLKFHH AEAVEARFAL
     LLQRRGWDAS FCRRGGLNCT TIGEEPVNLF YMFKDLAVLD VKATSLNLLH DDPEMLGYLE
     QIGDVAQEGN VLISPMDIQA YKLDLQPPSS QEE
//