ID A0A0E0CD06_9ORYZ Unreviewed; 476 AA.
AC A0A0E0CD06;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Uridine 5'-monophosphate synthase {ECO:0000256|ARBA:ARBA00015047};
DE EC=2.4.2.10 {ECO:0000256|ARBA:ARBA00011971};
DE EC=4.1.1.23 {ECO:0000256|ARBA:ARBA00012321};
OS Oryza meridionalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=40149 {ECO:0000313|EnsemblPlants:OMERI01G40820.5};
RN [1] {ECO:0000313|EnsemblPlants:OMERI01G40820.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OR44 {ECO:0000313|EnsemblPlants:OMERI01G40820.5};
RA Wing R.A., Panaud O., Henry R.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OMERI01G40820.5}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway;
CC UMP from orotate: step 1/2. {ECO:0000256|ARBA:ARBA00004889}.
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway;
CC UMP from orotate: step 2/2. {ECO:0000256|ARBA:ARBA00004861}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OMP decarboxylase
CC family. {ECO:0000256|ARBA:ARBA00009769}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the purine/pyrimidine
CC phosphoribosyltransferase family. {ECO:0000256|ARBA:ARBA00006221}.
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DR AlphaFoldDB; A0A0E0CD06; -.
DR STRING; 40149.A0A0E0CD06; -.
DR EnsemblPlants; OMERI01G40820.4; OMERI01G40820.4; OMERI01G40820.
DR EnsemblPlants; OMERI01G40820.5; OMERI01G40820.5; OMERI01G40820.
DR Gramene; OMERI01G40820.4; OMERI01G40820.4; OMERI01G40820.
DR Gramene; OMERI01G40820.5; OMERI01G40820.5; OMERI01G40820.
DR UniPathway; UPA00070; UER00119.
DR Proteomes; UP000008021; Chromosome 1.
DR GO; GO:0004588; F:orotate phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04725; OMP_decarboxylase_like; 1.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR HAMAP; MF_01208; PyrE; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014732; OMPdecase.
DR InterPro; IPR018089; OMPdecase_AS.
DR InterPro; IPR001754; OMPdeCOase_dom.
DR InterPro; IPR023031; OPRT.
DR InterPro; IPR004467; Or_phspho_trans_dom.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR NCBIfam; TIGR00336; pyrE; 1.
DR NCBIfam; TIGR01740; pyrF; 1.
DR PANTHER; PTHR19278; OROTATE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR19278:SF9; URIDINE 5'-MONOPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00215; OMPdecase; 1.
DR SMART; SM00934; OMPdecase; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
DR PROSITE; PS00156; OMPDECASE; 1.
PE 3: Inferred from homology;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Pyrimidine biosynthesis {ECO:0000256|ARBA:ARBA00022975};
KW Reference proteome {ECO:0000313|Proteomes:UP000008021}.
FT DOMAIN 245..463
FT /note="Orotidine 5'-phosphate decarboxylase"
FT /evidence="ECO:0000259|SMART:SM00934"
SQ SEQUENCE 476 AA; 50894 MW; F513593BE0C15A98 CRC64;
MDAAAQESLI LELHAIEAIK FGTFVLKSGI TSPIYLDLRA LVSHPGLLSS IASLLHSLPA
TRPYDLLCGV PYTALPIASV LSVHRSVPML MRRKEAKAHG TAKSIEGAFR AGEAVLIIED
LVTSGASVLE TAAPLRDQGL VVADAVVVVD REQGGRENLA ANGITLHSLM TLTEVLAVLL
KHGKVTEEKA REVRQFLDAN RKVTVPGAGA VKPKAVRKGF AERAGLAKNP MGKRLFEVME
AKQSNLCVAA DVGTAKELLE LAEKVGPEIC MLKTHVDILF DFTPDFGAKL RSIAEKHNFL
IFEDRKFADI GNTVTMQYEG GIFRILDWAD IVNAHIIPGP GIVDGLKLKG LPKGRGLLLL
AEMSSAGNLA HGEYTAAAVK IAEQHSDFVI GFISVNPASW SVAPSSPAFI HATPGVQMVS
GGDALGQQYN TPHSVINDRG SDIIIVGRGI IKASNPAETA REYRIQGWEA YQSSLS
//
