ID A0A0E0CRN4_9ORYZ Unreviewed; 487 AA.
AC A0A0E0CRN4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine--tRNA ligase {ECO:0000256|ARBA:ARBA00012815};
DE EC=6.1.1.21 {ECO:0000256|ARBA:ARBA00012815};
DE AltName: Full=Histidyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030619};
OS Oryza meridionalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=40149 {ECO:0000313|EnsemblPlants:OMERI02G31520.1};
RN [1] {ECO:0000313|EnsemblPlants:OMERI02G31520.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OR44 {ECO:0000313|EnsemblPlants:OMERI02G31520.1};
RA Wing R.A., Panaud O., Henry R.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OMERI02G31520.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-
CC histidyl-tRNA(His); Xref=Rhea:RHEA:17313, Rhea:RHEA-COMP:9665,
CC Rhea:RHEA-COMP:9689, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:57595, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78527, ChEBI:CHEBI:456215; EC=6.1.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00001137};
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR AlphaFoldDB; A0A0E0CRN4; -.
DR STRING; 40149.A0A0E0CRN4; -.
DR EnsemblPlants; OMERI02G31520.1; OMERI02G31520.1; OMERI02G31520.
DR EnsemblPlants; OMERI02G31520.2; OMERI02G31520.2; OMERI02G31520.
DR Gramene; OMERI02G31520.1; OMERI02G31520.1; OMERI02G31520.
DR Gramene; OMERI02G31520.2; OMERI02G31520.2; OMERI02G31520.
DR eggNOG; KOG1936; Eukaryota.
DR HOGENOM; CLU_025113_3_1_1; -.
DR Proteomes; UP000008021; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004821; F:histidine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00773; HisRS-like_core; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR HAMAP; MF_00127; His_tRNA_synth; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR015807; His-tRNA-ligase.
DR InterPro; IPR041715; HisRS-like_core.
DR InterPro; IPR004516; HisRS/HisZ.
DR NCBIfam; TIGR00442; hisS; 1.
DR PANTHER; PTHR43707:SF1; HISTIDINE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43707; HISTIDYL-TRNA SYNTHETASE; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF13393; tRNA-synt_His; 1.
DR PIRSF; PIRSF001549; His-tRNA_synth; 1.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008021}.
FT DOMAIN 75..397
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT REGION 22..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 54994 MW; 1A85281BFD48F0DD CRC64;
MAASASASLR HHLLLRRRPR FPLGPSPTFR TSSLPRRHQR LFASAPSSST VENGEPSSPV
EPSDGASVVD VNPPRGTRDF PPEDMRLRTW LFDQFREVSR VMAFEEVDFP VLESEALFIR
KAGEEITQQL YNFEDKGGRR VVLRPEITPS LARLVIKQGK SVSLPLKWFT IGQCWRYERM
TRGRRREHYQ WNMDIFGMPK VRAESELLQA IILLFERLGI TSSDVGIRVS SRKVLQAVLN
MYSVPEHLFT EVCVIVDKLG KLTREEIEKK LVTIGLSSEA VLGIIEVLSL KSLPKLEEVL
GSDVEAVADL KKLFSFAEQY GYADWICFDA SVVRGLAYYT GIVFEAFDRD GKLRAICGGG
RYDRLLSTFG SEDIPACGFG FGDAVIVELL KEKGLLPDLS RQIDDIVFPL DEELEGPACS
VASSLRRQGR SVDLVEDKRL KWVFKHAERI NAGRLILVGK SEWERGMVRV KILSTREEFE
VKAGELQ
//
