ID A0A0E0EYL8_9ORYZ Unreviewed; 5080 AA.
AC A0A0E0EYL8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Midasin {ECO:0000256|ARBA:ARBA00017143, ECO:0000256|PIRNR:PIRNR010340};
OS Oryza meridionalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=40149 {ECO:0000313|EnsemblPlants:OMERI10G09170.4};
RN [1] {ECO:0000313|EnsemblPlants:OMERI10G09170.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OR44 {ECO:0000313|EnsemblPlants:OMERI10G09170.4};
RA Wing R.A., Panaud O., Henry R.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OMERI10G09170.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- FUNCTION: Nuclear chaperone required for maturation and nuclear export
CC of pre-60S ribosome subunits. {ECO:0000256|PIRNR:PIRNR010340}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the midasin family.
CC {ECO:0000256|ARBA:ARBA00007188, ECO:0000256|PIRNR:PIRNR010340}.
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DR EnsemblPlants; OMERI10G09170.4; OMERI10G09170.4; OMERI10G09170.
DR Gramene; OMERI10G09170.4; OMERI10G09170.4; OMERI10G09170.
DR Proteomes; UP000008021; Chromosome 10.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR048617; MDN1_AAA_lid_4.
DR InterPro; IPR012099; Midasin.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 7.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 3.
DR Pfam; PF21108; MDN1_4th; 1.
DR PIRSF; PIRSF010340; Midasin; 5.
DR SMART; SM00382; AAA; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR010340};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR010340};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR010340};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR010340};
KW Reference proteome {ECO:0000313|Proteomes:UP000008021}.
FT DOMAIN 4876..5068
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 4246..4279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4319..4619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4631..4673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4687..4734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4247..4261
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4319..4342
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4353..4398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4429..4451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4452..4477
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4496..4534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4536..4619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4631..4658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4687..4713
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5080 AA; 574685 MW; 27F4E289F46AC3C1 CRC64;
MSLDGSFSAA AAAARLLARC PALRADPRVL ALASSTAGGG GGGPSRDDVA AALAEPLLHP
RYTVPVVGCF LPLAPALLDR AVGLLRAAGA AALRSDDPAA REGEEAGEGD LRVVEFYLSR
GRGLRLHEIA CLALARALDL APYLLRYLLN YFKFAPPPFQ RFLSGGVPSQ IPIKVGLHLL
LDATQVSYRF LELEPRVFCE QWDWSCFLDL VYSTADYSLV DDSLYSVVLD LRWCAIQILM
VVLKASDEAV ESFGLGADEA FTCFLRSFAQ ILPWRKPLCI FKPKKLIVKL MQMDSLVWLI
LCQIGMSFLW DGSMAVESYE VALMAVNQKW PILLYGPVGA GKTALINKLA QIGGNRVLFI
HMDEQMDGRT LIGSYVCTEK PGEFKWSPGS LTQAVEVAEN FRLFATVTTS KNDVSHALEG
RLTFSALWRK VMVGEPNRKD MIDIIHGCYP SLEPISAKLI DTFEKANLLV SYQFGGLNLA
GGSSECLVQR FSLRDLLKWC KRIRGVDLNF KGLGLSSSCC KLIYFEARHT DLQVGRVTLQ
CSDKPALIQK GPFADIRRAL EVLERVACSI KFNEPVLLVG ETGTGKTTLV QNLASWLKQP
LTVVNLSQQS DISDLLGGFK PADARSICFP LYIEFKDLFC RSFSGKDNEA ILRHCDVYVM
EKKWKKLLRA LEKCVEKAQK LIDGSSRSNS GSKRKRPLPA QVISDWDSFS SRLNAACSQI
GSEIGMSFQF VEGAFVSALR NGHWILLDEV NLAPPETLQR IGAVLDGESG TLCLAERGDV
DYIERHPCFR MFACMNPATD AGKRELPYTF RSRFTEFFVD DLIDDDDLRL FVSKYLDGLH
AAKGVADSIV RFYKAAKKES EEKLQDGANQ KPQFSLRSLS RSLGYIKNAE RKFGFKKALY
DGFCMFFLTM LDAPSAKIIN NLIVSLLLDG RVPPRISFAD YFVEKPKLLN GSESDDFLRS
YVLTNSVTEH IVNLARAVYI KKYPVLLQGP TSSGKTSLVR FLAAQTGHEF IRINNHEHTD
LQEYIGTYVT DSHGKLQFQE GALVKAVREG HWIVLDELNL APSDVLEALN RLLDDNRELF
VPELQETIPA HPNFMLFATQ NPPVLYGGRK ILSRAFRNRF IEVHVDEIPE DELITILEQR
CSIACSYATR MVQVMKDLQT HRQNSRVFAG KHGFITPRDL FRWANRYRLF EGKSYEDLAK
DGYLLLAERL RDDTEKAVVQ EVLEQHLHVK LSISNLYNME VSCDNNLSRE SIRLRVQETF
GNITWTESMW RLYFLIERCY RSREPVLLVG ETGGGKTTVC QVLSAVLGVK LHILNCHQYT
ETSDFIGGFC PIRDRSKIAM EFKHLITKMK QLKIFIHVAG DMSFPADISG AVSVVNHIDE
ILDRYIKEKE LFPQVPPHDF AAMEQIKLDL MQLHKRWQAI FLWQDGSLVQ AMKNGDLFLI
DEISLADDSV LERLNSVLEP ERKLSLAEKG GSVLEKVVAH PNFFILATMN PGGDYGKKEL
SPALRNRFTE VWVPAVTNVD ELKSIAIERF TNAEVSCFGD CIVNFWMWFN QLHTGRMLTI
RDLLSWISFI NVTERNLGPQ QALIHGLFLV LLDGLTLGMN VSKTEATELR RTCLSFLLEE
LQKVEGKPLN SDLHDLKNYG WGDHTREIDI GQPDHFGIMP FYIDTGHFTR KQQGFQFMAP
TTSKNVFRVL RGMQLPKPLL LEGSPGVGKT SLIVALAGFS GHNVVRINLS EQTDMMDLLG
SDLPVEGENG MEFAWSDGIL LQALKNGSWV LLDELNLAPQ SVLEGLNAIL DHRAEVFIPE
LGQTYKCPPS FRVFACQNPS SQGGGRKGLP KSFLNRFTKV YVDELSESDY SFICKSQYPS
IKDDILKKLI SFNNRLYMDT MIHKKYGQEG SPWEFNLRDI IRSCEMIVGA CETARGYPET
SMVDCFLNTV YLQRMRTVAD REEVVKLFEE VFQTNVWWLE VRLLEEIAST LAKFRIANST
FSLVPSIALK LPCTVSIKLS GNTLNEVNLS SATDVSELLG CFEQYNFFRH YKVVISQVER
YIDEYFSLSQ YIQWKSLVAD RKTLFVKWFE FVIAKKFSSI CISTIVEMSK NSSLPSLSLV
RDIVEDMKCD MEMFDLPVSF NKDDLSKTLR SIYYLQQSEA VHQPVKFEWV AGDLIRAIEC
GEWIVLDNAN FCNPTVLDRI NSLVEQERSI VVNECGLVDG NPVILKAHPK FRMFLTINAK
HGEVSRAMRN RGVEIFLMNQ NLSINGCSNA AEDSERRDIT RFLISCGIPR MELVSSMSEA
HLYAKAAGLH LGINITLLEI TRWVQLFKQL LIKGNQFLWS LHLSWEHTYL PSLGEVCSNI
VEEGKLRFLF PTVSDKQSVK PCVTGLFNSE LADQMLFIAA NWVMEQSTET DLKLYTIWFN
WCNHLLQPYC NFFENYGNIL KQESDHPIWH SILECYREIV AYHKIDVVAH PIPLLSMRLL
DMTCSVTLKD CHNRLRNSRN GLSLLQLTLQ QWQLETKFPD HGIMEVTMLP ALKSLRCLEG
EVLKMVVKSR KLLQIYSRLI DYHRSIWKMI LLSQFEGLPV VWNLLKKEIL KLQPKFPVEV
GIFLMESVNL NSLQDFNLHY DKPTLWVYGG HPIVPSSGRI FYKIQDILAF SSAVWPRKNL
LKGHFDDNQH FVDAMLSANQ DLRNLAMEGL SMASLAATIT EEEDSTVLAQ LDEVHKRLVE
KVDWEKKNLE VLSKASTTEI IANIEYMLKY AMDFQLGSSS RSPFEFTQHQ IIWWIHHAWA
TVDNAYKLAL ECSAVHVQFS VTHDETCDLA HLTKMDAIDT ILQEDLRVMD YQKNRLVLRI
SSRNLWEGVS FAGNFVLSLH SAADSLFKQI IVVHKKHFKQ EEYSKLESIL FQQSEHRVKK
EDLDTACALL SRSSHGVLAS LAGSHELIGS LLLELHSPFS QGYLMHLGAA WVYIGELRFR
LLLSSYNPDP AFESAFMHSH ILEKISLLEL EGKVRHQCEE LAGSSSAEDG YDQKLLQELK
TKEKSIRAKV VFRPPQSRHK SLIAACCEFE ERLSECKSLL TSLNGDGVGQ LEIDRVCNWQ
ITSRNFIKRL TEEYVEYVDL IQPIQVAVYE MKLGLAIALS GYLEREYLKK IKEDDIELAL
GAIFAIMQFP SGSATGNVSV DMPDLTKYVN DDQLEIRYNE VSDLAMLKKL AAVSSQLHVG
EVADKLRSHS QMLVSIHHIS LVRTTYRVCY SLILDKTSYL SLKETFDQFT SMWVDMKSSL
KARENDDSQY YKFRSRIIDI HDIFKGDVPS LSDMDAEGNA VADTEEKLEQ DFLKIMERTD
EENSAVEDSW DLIPESILKC IVTIHNQLFG SPDLVEKPSK CQISDDLKIQ SFMDSYQLGA
RILKDLPELT SSTFDEKLMP EHLLRVCLEY RQTCAPSLEC NTYNAYKDPN PSILFKMVEP
LTALQEKVRY FLDEWPGHPG LLKILDIITS LLAIPLSTPL SKVLLGLQLL VGKAQTLQEN
DSKFFLKDHL PQLFIIVSSW QRLELECWPI LLQEVLEKYE SNALKLWFPL RALLTQSCDI
SKNEEISIIK SVEEFVQTSS IGEFKRRLHL LLAFHGELSD GAGVGAYSSN SLKKIQNILY
NMFGYYMQFL PLVLGEIEGG KGSIEKDLKD QVKLYRWEQD PHSASIENFK RTRQKVFKLL
QRFNDILQKP VMILLNQESV ARKVPCWLDQ QMPESEFPVD LGKLSGRFLW YTKWANQAKL
SFQALQHTNA TDIGVHNEEF ARVVFHNTNC QQAESELEDR LNFFWAAIER ICNAADFGSI
LKSGKKNQKK TALSNLFKTL EECGLSKHRP MGREGNELAA PSPFLEQSYI TTHLLQQVIS
KKMPEDASVA HATLLSTNNW KNANQQYFKC LAMMQQLRQI SLKFNKDLGL EEVNRATSFM
DHLLSIMSEQ RHFAYNMFEQ LNEFRHAILL LGSGGDSDYL SSCQSVLLNS MWQQKQFFDN
ILATTMDTNL LLRSFIDCHH DPCDNIQVEV SAMSTLFEKF IARFSESKDL LDKYLLGSNY
MIAGSHKNMP LATREMEQLV AANCQLISMF REDIQVLCHQ DVSMRSVKKV LLSRFEELLE
KGNSPMAILS RKVDEDKHML SSDVLHNLEA SYAEALKEIF SLAVGVVGKL TDQGISTDGT
HDSLEGNITL WKDILQTYVM NLQMGHLFDA SKKLTVSVRR LVNIKPELRS SIGMQLMHLH
ALLGLVLSAA EGILSELLEA HRTTSEMTHA LGDLLIHLFA EGFGSTDDTT EDASDGPQQD
ATGTGMGEGE GKESASSKID DISQLEGTAN EMDALRKPDQ APKNDDDAVE MQDDFNAELS
DVSEDPEGND SGDEDDDTNL ENQMGDTGDA SEMVGKKSWD KDEDDDPNRS TEKYESGSSA
KETQKNDREL RAKDEGALEE DPMETDCDEQ GKNNNLEDDP STCEDVDQDT NDLMDKADAY
DDRTAPELPE PKDDSEDVDM DGTEHIDEMD ADGEELSPEE EKLAADGSLD ASDDVEDVDA
AQHGDNEIDG EQEHAEDGQM ETNNMEKELH NIESLEHPSQ GIQPNNAEMD YNRESESNLA
NSTDMNSAAA PSVNFSSNEV PSLEISMPNS GDGSRLLSNS KPELQTDTPP SQIKQTNPFR
SIGDAMADWK ERAKVSADTQ DHQPEAEHHI DDESATEFRY VPGSEQSTSQ ALGNATADQI
NDDLQVKQSS MEDENRVQKE EHNTDRAPGD DHNLEVPHLQ ASQSRTNKSE NANNLEHREI
QTDTYVQDSV QGETDKTFGD FVSFKQPPAD EKTVMRDDLA NDRELSTPME INITDVDMKV
PIVDWKSVEL TTMKLSQELA EQLRLVMEPT LASKLQGDYR TGKRINMKKV IPYIASHFRR
DKIWLRRTKP NKRNYQVVIA VDDSRSMSEG KCGKVAIEAL VTVCRAMSQL EVGQFAVASF
GKKGNVKVLH DFDQVFNGEA GTNQDNKLED EPVADLLMHL NTMLDTAVAR SRTPSGQNPL
QQLVLIISDG KFHEKENLKR CVRNVLNRKR MIAYVLLDGH EESIMDSLEV SYQGTKLTMG
KYMDSFPFPY YVMLKNIEAL PRTLADLLRQ WFELMQSANE
//
