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Database: UniProt
Entry: A0A0E0GFS1_ORYNI
LinkDB: A0A0E0GFS1_ORYNI
Original site: A0A0E0GFS1_ORYNI 
ID   A0A0E0GFS1_ORYNI        Unreviewed;       947 AA.
AC   A0A0E0GFS1;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   31-JUL-2019, entry version 20.
DE   RecName: Full=Arogenate dehydratase {ECO:0000256|RuleBase:RU363004};
DE            EC=4.2.1.91 {ECO:0000256|RuleBase:RU363004};
OS   Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=4536 {ECO:0000313|EnsemblPlants:ONIVA03G00790.3, ECO:0000313|Proteomes:UP000006591};
RN   [1] {ECO:0000313|EnsemblPlants:ONIVA03G00790.3, ECO:0000313|Proteomes:UP000006591}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA03G00790.3,
RC   ECO:0000313|Proteomes:UP000006591};
RA   Wing R.A., Hsing Y.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ONIVA03G00790.3}
RP   IDENTIFICATION.
RC   STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA03G00790.3};
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC       chorismate pathway into phenylalanine.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC         Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180;
CC         EC=4.2.1.91; Evidence={ECO:0000256|RuleBase:RU363004};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC       phenylalanine from L-arogenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000256|RuleBase:RU363004}.
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DR   EnsemblPlants; ONIVA03G00790.3; ONIVA03G00790.3; ONIVA03G00790.
DR   Gramene; ONIVA03G00790.3; ONIVA03G00790.3; ONIVA03G00790.
DR   UniPathway; UPA00121; UER00344.
DR   Proteomes; UP000006591; Chromosome 3.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0047769; F:arogenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001171; Ergosterol_biosynth_ERG4_ERG24.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   InterPro; IPR018083; Sterol_reductase_CS.
DR   Pfam; PF01222; ERG4_ERG24; 1.
DR   Pfam; PF00800; PDT; 2.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
DR   PROSITE; PS01018; STEROL_REDUCT_2; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Chloroplast {ECO:0000256|RuleBase:RU363004};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006591};
KW   Lyase {ECO:0000256|RuleBase:RU363004};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Plastid {ECO:0000256|RuleBase:RU363004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006591};
KW   Transit peptide {ECO:0000256|RuleBase:RU363004};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     56     75       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     87    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    119    139       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    178    196       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    202    220       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    240    264       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    270    289       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      556    747       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      729    820       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   REGION      441    481       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   947 AA;  106027 MW;  11410508B5EE41EF CRC64;
     MDAAAVAASL VPSWSAVLVL FSYLGYLAAA GAVLPGKLVP GAVLPDSSRL HYRCNGTASA
     ALALLLYAFF DAVLFSHLMR ACVTRAGLLS LLLLLVLSAL GVYMGWMSPT VIADRGIELL
     STTFIFSVIV TFLLYYSGLR SHHKSSSLKP HITGNFIQDW WLGVQLNPHF MGVDLKFFFV
     RAGMMAWLFI NLSLFAKSYL AGSANLSVIL YQFFCAWYIV DYFVHEEFMT STWDIIAERL
     GFMLVFGDLV FIPFTFTIQG WWLLRNKVEL SLLAAVVNCF IFVIGYLVFR GANKQKHIFK
     KNPKALIWGK PPKLVGGKLL VSGYWGIARH CNYLGDILLA LSFSLPCGTS SVIPYFYPTY
     LFILLIWRER RDEARCSEKY KEIWVEYCKL VPWRIFPYVL AGEHLILFSR RRRGVSSPPT
     ATFLLLLSFH LHYPSPRLAA RRRPFPPPTP RRARLASGDR RRMETSPAPR PAHIPRSTAV
     RPPCATPFSR AHWHTTCAAI RRVPRVNGDS NSSIKPALSD HAAPPLDLDL LPVSNLPRPL
     TITDLSPAPM HGSQLRVAYQ GVPGAYSEAA AAKAYPSCDA IPCDQFEVAF QAVELWIADR
     AVLPVENSLG GSIHRNYDLL LRHRLHIAEH AVELWIADRA VLPVENSLGG SIHRNYDLLL
     RHRLHIAEHV AAAGLRDTAA IASSRAAELY GLQVLADGIQ DDAGNVTRFV MLAREPIIPR
     TDRPFKTSIV FAHDREGTSV LFKVLSAFAF RDISLTKIES RPHRHRPIRL VDDANVGTAK
     HFEYMFYIDF QASMAEVRAQ NALSEIQEFT SFLRVLGSYP MDMTPWEYSS SSLLDVAGAG
     EKLQANIRLA SGMTRILAIF LGPWIQRING AEGIPPTMRI AFSFCREHMW SIKTCADTPF
     LLLGCGAFSL RRRLKLSMAA MRCLQLQSSE ASETFYDWDA WEALPSL
//
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