ID A0A0E0GJ87_ORYNI Unreviewed; 577 AA.
AC A0A0E0GJ87;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=2-hydroxyacyl-CoA lyase {ECO:0008006|Google:ProtNLM};
OS Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4536 {ECO:0000313|EnsemblPlants:ONIVA03G09800.1};
RN [1] {ECO:0000313|EnsemblPlants:ONIVA03G09800.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA03G09800.1};
RA Wing R.A., Hsing Y.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ONIVA03G09800.1}
RP IDENTIFICATION.
RC STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA03G09800.1};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812, ECO:0000256|RuleBase:RU362132}.
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DR AlphaFoldDB; A0A0E0GJ87; -.
DR STRING; 4536.A0A0E0GJ87; -.
DR EnsemblPlants; ONIVA03G09800.1; ONIVA03G09800.1; ONIVA03G09800.
DR Gramene; ONIVA03G09800.1; ONIVA03G09800.1; ONIVA03G09800.
DR eggNOG; KOG1185; Eukaryota.
DR HOGENOM; CLU_013748_3_3_1; -.
DR OMA; PGPYGCL; -.
DR Proteomes; UP000006591; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd02004; TPP_BZL_OCoD_HPCL; 1.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR045025; HACL1-like.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR000399; TPP-bd_CS.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR43710; 2-HYDROXYACYL-COA LYASE; 1.
DR PANTHER; PTHR43710:SF2; 2-HYDROXYACYL-COA LYASE 1; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS00187; TPP_ENZYMES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006591};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}.
FT DOMAIN 18..128
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 211..337
FT /note="Thiamine pyrophosphate enzyme central"
FT /evidence="ECO:0000259|Pfam:PF00205"
FT DOMAIN 409..560
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 577 AA; 60768 MW; B5CDF976CB2A2CC0 CRC64;
MATDTAAPAA MKVDGSALAG RALAAAGARH MFGVVGIPVT SLASRAAAAG VRFLAFRNEQ
SAGYAAAAYG FLTGSPGLLL TVSGPGCVHG LAGLSHATAN AWPLLMVSGS CSQPDAGRGD
FQELDQIAAT KPFVKIAVKA TTIADIPRLV FQALAATVSG RPGGCYLDIP SDVLHQTLTE
SEAAALIDAA AADSAKSDSS PPKHKSLDEG IEKAAELLRR AERPLVVFGK GAAYSRAEDA
IRKLVDTTGI PFLPTPMGKG VVPDTHPLSA TAARSLAIGQ CDVALVVGAR LNWLLHFGEP
PKWSKDVKFI LVDVCEEEIE LRKPHVGIVG DAKRVVELIN REIKDQPFCL APSHPWVEAI
TKKARDNVLK MEAQLAKDVV PFNFLTPLRI IRDAILAEGN PAPVVVSEGA NTMDVGRAVL
VQNEPRTRLD AGTWGTMGVG LGFCVAAAVA EPDRLVVAVE GDSGFGFSAM EVETLVRYQL
PVVVIVFNNN GVYGGDRRSP DEITGPYKDD PAPTSFVPAA GYHNMMEAFG GKGYLVETPD
ELKSALSESF RARKPAVINV IIDPYAGAES GRMQHKN
//
