ID A0A0E0H2B5_ORYNI Unreviewed; 473 AA.
AC A0A0E0H2B5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=glucose-6-phosphate dehydrogenase (NADP(+)) {ECO:0000256|ARBA:ARBA00013019};
DE EC=1.1.1.49 {ECO:0000256|ARBA:ARBA00013019};
OS Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4536 {ECO:0000313|EnsemblPlants:ONIVA04G14690.2};
RN [1] {ECO:0000313|EnsemblPlants:ONIVA04G14690.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA04G14690.2};
RA Wing R.A., Hsing Y.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ONIVA04G14690.2}
RP IDENTIFICATION.
RC STRAIN=SL10 {ECO:0000313|EnsemblPlants:ONIVA04G14690.2};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-
CC lactone + H(+) + NADPH; Xref=Rhea:RHEA:15841, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:57955, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:61548; EC=1.1.1.49;
CC Evidence={ECO:0000256|ARBA:ARBA00000740};
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 1/3. {ECO:0000256|ARBA:ARBA00004937}.
CC -!- SIMILARITY: Belongs to the glucose-6-phosphate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009975}.
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DR AlphaFoldDB; A0A0E0H2B5; -.
DR EnsemblPlants; ONIVA04G14690.2; ONIVA04G14690.2; ONIVA04G14690.
DR Gramene; ONIVA04G14690.2; ONIVA04G14690.2; ONIVA04G14690.
DR UniPathway; UPA00115; UER00408.
DR Proteomes; UP000006591; Unassembled WGS sequence.
DR GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0009051; P:pentose-phosphate shunt, oxidative branch; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR HAMAP; MF_00966; G6PD; 1.
DR InterPro; IPR001282; G6P_DH.
DR InterPro; IPR019796; G6P_DH_AS.
DR InterPro; IPR022675; G6P_DH_C.
DR InterPro; IPR022674; G6P_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR23429:SF8; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE; 1.
DR PANTHER; PTHR23429; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD; 1.
DR Pfam; PF02781; G6PD_C; 1.
DR Pfam; PF00479; G6PD_N; 1.
DR PIRSF; PIRSF000110; G6PD; 2.
DR PRINTS; PR00079; G6PDHDRGNASE.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00069; G6P_DEHYDROGENASE; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006591}.
FT DOMAIN 33..210
FT /note="Glucose-6-phosphate dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF00479"
FT DOMAIN 233..458
FT /note="Glucose-6-phosphate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02781"
FT BINDING 205
FT /ligand="substrate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10005"
SQ SEQUENCE 473 AA; 53960 MW; E014E6DDB99018ED CRC64;
MSGGSSPRSR RSSFNSLSRD LELPSEQGCL SVIVLGASGD LAKKKTFPAL FHLFAQGFIQ
SGEVHIFGYA RSNLSDDGLR ERIRGYLKGA SEEHLSDFLQ HIKYVSGSYD SGEGFEKLNK
EISEYEKSNK SESPRRLFYL ALPPSVYPSV CKMIRTYCMN PSGWTRVIVE KPFGKDLDSA
EELSAQLGEL FDENQLYRID HYLGKELVQN LLVLRFANRL FLPLWNRDNI DNIQVFCLVA
MEKPVSLKPE HIRDEKVKVL QSVNPIKHDE VVLGQYEGYK DDPTVPDDSN TPTFASVVLR
VHNERWEGVP FILKAGKALS SRKAEVRVQF KDVPGDIFKC KRQGRNEFVI RLQPSEAMYM
KLTVKKPGLE MATEQSELDL SYGMRYQNVK IPEAYERLIL DTIRGDQQHF VRRDELKAAW
QIFTPLLHDI DEGKVKSIPY QPGSRGPKEA DELSERVGYM QTHGYIWIPP TLA
//
