ID   A0A0E0K2Y6_ORYPU        Unreviewed;       489 AA.
AC   A0A0E0K2Y6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Legumain prodomain domain-containing protein {ECO:0000259|Pfam:PF20985};
OS   Oryza punctata (Red rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC02G23580.1};
RN   [1] {ECO:0000313|EnsemblPlants:OPUNC02G23580.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wing R.;
RT   "Oryza genome evolution.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:OPUNC02G23580.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
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DR   AlphaFoldDB; A0A0E0K2Y6; -.
DR   STRING; 4537.A0A0E0K2Y6; -.
DR   MEROPS; C13.001; -.
DR   EnsemblPlants; OPUNC02G23580.1; OPUNC02G23580.1; OPUNC02G23580.
DR   Gramene; OPUNC02G23580.1; OPUNC02G23580.1; OPUNC02G23580.
DR   eggNOG; KOG1348; Eukaryota.
DR   HOGENOM; CLU_024160_0_0_1; -.
DR   OMA; NTWDNYR; -.
DR   Proteomes; UP000026962; Chromosome 2.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR   CDD; cd21115; legumain_C; 1.
DR   Gene3D; 1.10.132.130; -; 1.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR043577; AE.
DR   InterPro; IPR048501; Legum_prodom.
DR   InterPro; IPR046427; Legumain_prodom_sf.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR12000:SF54; VACUOLAR-PROCESSING ENZYME BETA-ISOZYME; 1.
DR   Pfam; PF20985; Legum_prodom; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PIRSF; PIRSF500139; AE; 1.
DR   PIRSF; PIRSF019663; Legumain; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026962};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..489
FT                   /note="Legumain prodomain domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002364962"
FT   DOMAIN          377..472
FT                   /note="Legumain prodomain"
FT                   /evidence="ECO:0000259|Pfam:PF20985"
FT   ACT_SITE        173
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        215
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   489 AA;  54249 MW;  AD82B9C4693B9BCB CRC64;
     MAARWCFALL LALSAAAGAG AKRTWEPLIR MPGEVVVEEE ASEGTEEEED GVGTRWAVLV
     AGSSGYGNYR HQADVCHAYQ ILQKGGLKEE NIVVFMYDDI ANNVLNPRPG VIVNHPQGED
     VYAGVPKDYT GDEVTAKNFY AVLLGNKTAV TGGSRKVIDS KPNDHIFIFY SDHGGPGVLG
     MPNLPYLYAA DFMKVLQEKH DSNTYAKMVI YVEACESGSI FEGLMPEDLN IYVTTASNAD
     ESSWGTYCPG MEPSPPSEYI TCLGDLYSVS WMEDSETHNL KEESIKKQYE VVKKRTSDMN
     SYGAGSHVME YGDRTFKDDK LYLYQGFDPA NAEVKNKLSW EGPKAAVNQR DADLLFLWRR
     YELLHDKSEE KLKALREISD TVMHRKHLDS SVDLVGKLLF GFGNGPSMLQ AVRPSGQPLV
     DDWDCLKRMV RIFESHCGPL TQYGMKHMRA FANICNNGIS GASMKEASIA TCNSYNSGRW
     SSLVQGYSA
//