ID A0A0E0L6Y7_ORYPU Unreviewed; 1185 AA.
AC A0A0E0L6Y7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=4-coumarate--CoA ligase {ECO:0000256|ARBA:ARBA00012959};
DE EC=6.2.1.12 {ECO:0000256|ARBA:ARBA00012959};
OS Oryza punctata (Red rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC06G00750.1};
RN [1] {ECO:0000313|EnsemblPlants:OPUNC06G00750.1}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OPUNC06G00750.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-4-coumarate + ATP + CoA = (E)-4-coumaroyl-CoA + AMP +
CC diphosphate; Xref=Rhea:RHEA:19641, ChEBI:CHEBI:12876,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:85008, ChEBI:CHEBI:456215; EC=6.2.1.12;
CC Evidence={ECO:0000256|ARBA:ARBA00034252};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19642;
CC Evidence={ECO:0000256|ARBA:ARBA00034252};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-4-coumarate + ATP + H(+) = (E)-4-coumaroyl-AMP +
CC diphosphate; Xref=Rhea:RHEA:72419, ChEBI:CHEBI:12876,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:192348; Evidence={ECO:0000256|ARBA:ARBA00034219};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:72420;
CC Evidence={ECO:0000256|ARBA:ARBA00034219};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-4-coumaroyl-AMP + CoA = (E)-4-coumaroyl-CoA + AMP + H(+);
CC Xref=Rhea:RHEA:72423, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:85008, ChEBI:CHEBI:192348, ChEBI:CHEBI:456215;
CC Evidence={ECO:0000256|ARBA:ARBA00034223};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:72424;
CC Evidence={ECO:0000256|ARBA:ARBA00034223};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR AlphaFoldDB; A0A0E0L6Y7; -.
DR STRING; 4537.A0A0E0L6Y7; -.
DR EnsemblPlants; OPUNC06G00680.1; OPUNC06G00680.1; OPUNC06G00680.
DR EnsemblPlants; OPUNC06G00750.1; OPUNC06G00750.1; OPUNC06G00750.
DR Gramene; OPUNC06G00680.1; OPUNC06G00680.1; OPUNC06G00680.
DR Gramene; OPUNC06G00750.1; OPUNC06G00750.1; OPUNC06G00750.
DR eggNOG; KOG1178; Eukaryota.
DR eggNOG; KOG4649; Eukaryota.
DR HOGENOM; CLU_008297_0_0_1; -.
DR OMA; NGNVICC; -.
DR Proteomes; UP000026962; Chromosome 6.
DR GO; GO:0016207; F:4-coumarate-CoA ligase activity; IEA:UniProt.
DR GO; GO:0106290; F:trans-cinnamate-CoA ligase activity; IEA:UniProt.
DR GO; GO:0009698; P:phenylpropanoid metabolic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 2.40.10.480; -; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR44394; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44394:SF1; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF13360; PQQ_2; 2.
DR Pfam; PF13570; PQQ_3; 1.
DR SMART; SM00564; PQQ; 5.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT DOMAIN 98..417
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 470..558
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 1185 AA; 130183 MW; A8B75D66A49B5B07 CRC64;
MAAAAAAAKE EEPCCISHAF DRAARRNPNG LAVIHAASSS SSSGSESERR FTCADLLAAV
SSLSRRIAAE LRSYTSRHRD ESPGCSGRPV EAAAAPRIVG VYASPSVEYI AAVLAVLRCG
EAFLPLDPSW PEERIRWATS SSNAALVVSS RGSGAAHVFA SNACSVIRMD DDLWQVFEDE
KGGISREELA WPCKCKKPRE FCYVMFTSGS TGKPKGVCGT EKGLLNRFLW MQRWKPLCPD
DLLLFKTSVS FVDHLQEFLS AMLTCTTLVI PPPNDWRANP ASLANLIKAY GISRMTLVPS
LMEIILPTLE KNLSWGHNPL KMLIFSGENL SILLWKKVHE ILPETTIVNL YGTTEVSGDC
TFFDCTDLPT LLKREELTSV PIGFPISNCE VCIATDFEVA DEGEMHVTGA CLFAGYLEES
MVNSHTEGNG SSTYYRTGDF ARRLKSGEFI FLGRKDRTVK IYGQRFSLQE VESTLKEHPD
VSAAAVTFQN NGSLDFRAYL VLKNSAASEE DCQQRKKYKY SQVIMPSIRS WLVMKLPPAM
IPRFFLPVES LPLTSSGKTD YVKLSSLKCA LESCEFETER HTVNPHLQVI KKAFSDALLV
DEVSEFDDFF TLGGNSISAA HVAHRLEIDM RMLYIYSTPS KLLDALFTKH SSLLSSGHEP
HPKKGLDISS SILSSFNLIA TSVYDNFPEG KAHINGDGEC AHDHISGNYA NEVDGQLNRN
VHLSNDRYQT KSLLLDTYSN DRNSVDGSPW ILNFCLQKKW SLGRCNRFMH GYEDNLQIED
VCSYVPYNKR GYLQALWNIP LGSCVDASPL LVSNNGMLNI FVGSHSHTFL CIDGCSGSVR
WSVKLEGRVE CSAAITGDFS EVTQQQTPLR IYLAFWQPVH GSTSFGQVVV GCYKGKIYFL
DMLTGTQDWT IQTDGENVVA VHFSESQIEV SIFVFRCGSY DHHLYALNYK DRCCTYKISC
GGSIYGSPAI DMTHNMIYVA STSGLVTAIS LEVSSFRIVW QYEAGAPIFG SLAIHHQSGK
VICCLVNGLV IALNSHGSVV WKATVGGPIF AGACLSSGLP NQVLIPSRDG RLYSFDTTSG
ALLWKYEVGD PITASAFVDD VLIATSPGSS ERFACICTSS GQVHVIRIRA DAKQEKVNGS
VCNDLVQGFA AIDLPGDIFS SPLMVGGRIF VGCRDDQLHC LTISP
//
