ID A0A0E0LE72_ORYPU Unreviewed; 580 AA.
AC A0A0E0LE72;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=phosphoglycerate dehydrogenase {ECO:0000256|ARBA:ARBA00013143};
DE EC=1.1.1.95 {ECO:0000256|ARBA:ARBA00013143};
OS Oryza punctata (Red rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC06G21050.1};
RN [1] {ECO:0000313|EnsemblPlants:OPUNC06G21050.1}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OPUNC06G21050.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+)
CC + NADH; Xref=Rhea:RHEA:12641, ChEBI:CHEBI:15378, ChEBI:CHEBI:18110,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:58272; EC=1.1.1.95;
CC Evidence={ECO:0000256|ARBA:ARBA00001878};
CC -!- PATHWAY: Amino-acid biosynthesis; L-serine biosynthesis; L-serine from
CC 3-phospho-D-glycerate: step 1/3. {ECO:0000256|ARBA:ARBA00005216}.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854}.
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DR AlphaFoldDB; A0A0E0LE72; -.
DR STRING; 4537.A0A0E0LE72; -.
DR EnsemblPlants; OPUNC06G21050.1; OPUNC06G21050.1; OPUNC06G21050.
DR Gramene; OPUNC06G21050.1; OPUNC06G21050.1; OPUNC06G21050.
DR eggNOG; KOG0068; Eukaryota.
DR HOGENOM; CLU_019796_8_1_1; -.
DR OMA; ERIFHDD; -.
DR UniPathway; UPA00135; UER00196.
DR Proteomes; UP000026962; Chromosome 6.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd04902; ACT_3PGDH-xct; 1.
DR CDD; cd12173; PGDH_4; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR029009; ASB_dom_sf.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR045626; PGDH_ASB_dom.
DR PANTHER; PTHR42938:SF49; D-3-PHOSPHOGLYCERATE DEHYDROGENASE; 1.
DR PANTHER; PTHR42938; FORMATE DEHYDROGENASE 1; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF19304; PGDH_inter; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF143548; Serine metabolism enzymes domain; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT DOMAIN 508..580
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 580 AA; 60704 MW; 147689A72C0614C0 CRC64;
MALAAPLCHL LAAPAPPSTS HAADAAHDPA HHRASPLRRR GRGRLFLACR IPAAAPSARG
AAAGVAAAAA TAAGRPTVLV TEKLGDAGLE LLRRFANVDC AYELTAEELR AKVSLVDALV
VRSATRVTRE VFEAARGRLR VVGRAGVGID NVDLQAATEA GCLVVNAPTA NTVAAAEHAI
ALLAAMARNV AQADASLKAG KWQRNKYVGV SLVGKTLAIM GFGKVGSEVA RRAKGLGMDI
IAHDPYAPVD RARAIGVDLV SFDEAISTAD FISLHMPLTP STAKLFDEET FANMKKGVRI
INVARGGVVD EDALLRALDN GTVSQEGVAL EIAEAVLGAL KGELAATAVN APMVPAEVLS
ELSPYVVLAE KLGRLVVQLV AGGSGIKGVK IVYSSSRDPD DLDTRVLRAM VTKGIIEPIS
SAFVNIVNAD YVAKQRGLRI SEERILLDGS PEVPIDSIQV HLANVESKFA GALSDEGDIR
VEGEVKDGKP HLTLVGPFSV DVSLEGNLIL CRQVDQPGII GKVGSILGKM NVNVNFMSVG
RTAPGKQAIM AIGVDEEPEK EALKLIGDIP SVEEFVFIKL
//
