ID   A0A0E0PCP7_ORYRU        Unreviewed;       963 AA.
AC   A0A0E0PCP7;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI04G23370.8, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI04G23370.8}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A0E0PCP7; -.
DR   EnsemblPlants; ORUFI04G23370.8; ORUFI04G23370.8; ORUFI04G23370.
DR   Gramene; ORUFI04G23370.8; ORUFI04G23370.8; ORUFI04G23370.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015918; P:sterol transport; IEA:UniProt.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR032190; NPC1_N.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR45727; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR   PANTHER; PTHR45727:SF2; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR   Pfam; PF16414; NPC1_N; 1.
DR   Pfam; PF02460; Patched; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           38..963
FT                   /note="SSD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002369860"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        659..682
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          534..609
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   963 AA;  106158 MW;  E340426B623DA4F4 CRC64;
     MALVRRRRGV AGGGGPALAA VAVALMQLVF LVPPTRAQQS NGTSRVVPAE GYCSMYGICA
     QRSDGKVLNC VNATKAVKPD TLFSARIQSL CPTITGDVCC TVDQFDTLHQ QVQQAIPFLV
     GCPACLRNFL NLFCEMSCSP NQSLFINVTS VKQVNNTMTV NGIDYYVTST YGEELYNSCK
     DVKFGTLNTR AMDFLGGGAK NYKEWMAFIG RQADLNQIGS PYLITFPSDI SGSTAAKCLD
     FSLVVVYLVL LTRRSGIFSH TKPLKNAEDK IHSSNNGKVP DSSAQVSEAA SAPVQSAHPS
     VIQTYMSTFF RKHGTFVAKH PLLVLFVSLL VPTLLCIGLI RFKVEIRPEK LWVSSGSRAA
     DEKQYFDSHL APFYRIEQLV LATSAFGGSE APTIVNDNNM KLLFQIQKKY FQLDPKKYDD
     SGIDHAKFCF QHYTTEETCL STFQSPIDPS TILGGFPGNN FTEASAFVIT YPVNNKVETT
     GQENGKAVAW ERAYVNLVKE EILPMVLAHN LTMSFSSESS IQDELNREST ADAITIVVGV
     DNMCILVHAV KRQPDGLDLE ERISTALVEV GPSITLASLA EVLAFAVSAI NPMPATRVFS
     MFAAFVALIV LDFRRAQDGR IDCMPCARVK SSVVASDGGN HQGLPLLARY MKNVHAPILG
     YRAVKFVVIA VFVGFSFASI ALSTRLQPGL EQKIVLPRDS YLQDYFDDLA TYMKVGPPLY
     FVIKNFNYSS ASEHTNKICS INQCDSNSLL NETCIMDAHP QLNSKRNFHG FLTHFRQVIV
     LRVAKELILQ VWTLTSDYVN SMKAARDFSS KMSKELQGMM AILGIQLNAI SIVNLVMSIG
     IAVEFCVHIT HAFMALEIEK AVQGKLYRRW GLLYSGCSEF VWPPFKGDET SRTESTFSFV
     RVKLTTGEFT QLNISTPDRD TWKSAILKLA EHPCGHPSLL VRSSSAVYSI SRGASHFILY
     LDS
//