ID A0A0E0PE31_ORYRU Unreviewed; 4573 AA.
AC A0A0E0PE31;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI04G26970.5, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI04G26970.5}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EnsemblPlants; ORUFI04G26970.5; ORUFI04G26970.5; ORUFI04G26970.
DR Gramene; ORUFI04G26970.5; ORUFI04G26970.5; ORUFI04G26970.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 4.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 5.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 5.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF41; OS04G0616500 PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF11721; Malectin; 5.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 2.
DR Pfam; PF00069; Pkinase; 3.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 5.
DR SUPFAM; SSF52058; L domain-like; 4.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 5.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 4.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 5.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..4573
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002370069"
FT TRANSMEM 427..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 851..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1807..1826
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2294..2316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 4181..4205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 486..747
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1448..1725
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 2352..2626
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 3321..3595
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 4241..4503
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 763..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4525..4573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4525..4564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 1476
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT BINDING 2380
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT BINDING 3349
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT BINDING 4269
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 4573 AA; 502329 MW; FE91005A805B1BB5 CRC64;
MALSVLLLLL AAVAQAQKAP TATTDRIEAE ALKAVFEKLD QKAEWNTTGD PCSGAATDST
DINDSSINPA IKCDCSDQNN TVCHITGLKS HILSLEHTRT FGINALSGSI PKELGNLTNL
VSLYIDSAGL SGELPSSLSK LTRMKILWAS DNNFTGQIPD YIGSWNLTDL RFQGNSFQGP
LPANLSNLVQ LTNLILRNCM ISDSLALIDF SKFATASFAV DCGSTRFISG SRNSSYQADA
TNLGAASYHV TEPLTWGISN VGKFMDTPNG TTIINNARQF QATLDSELFQ TARMSPSSLR
YYGIGLQNGN YTVSLQFAEF GFEDTESWKS RGRRVFDIYV QGERKEKDFD IKKEAGGKSY
TAVKKDYIVS VTKNFVEIHL FWAGKGTCCI PTQGYYGPTI SALSLSPNFT PTIGNVAEQN
SSTSKTVVIV AVAIGVTILG LVALVGIFLW RKKRRKLSLE QQELYSIVGR PNIFSYGELR
SATENFSSSN RLGEGGYGAV YKLSQTSHQG KKQFATEIET ISRVQHRNLV KLYGCCLEGN
NPLLVYEYME NGSLDKALFG TEKLHIGWPA RFEICLGIAR GLAYLHEESS IRVVHRDIKA
SNVLLDANLN PKISDFGLAK LYDDKMTHVS TKVAGTFGYL APEYAMRGHM TEKVDVFAFG
VVLLETLAGR PNYDDVLEED KIYIFEWVWR LYESERALDI VDPNLTEFNS EEVLRAIHVA
LLCTQGSPHR RPSMSRVVAM LTGDAEVGEV AAKPSYITEW QIKGGGTTTT TTGSSSTSSS
AANGQWSSAP PPPRATSSPK MSSPFLSSVV DEGSCLEEPC VGGDRERRLT AQLRREREMR
RFIRSRVRRQ IHLHGSVLLI ILLLLAAAVA QAQQAPTTRT DPTEAAALNA VFAKLGQKAQ
PSWNITGDPC TGRATDGSST EDDSFNPAIT CDCTDQNGTV CHITKLKIYA MDASGPIPEE
LRNLTRLTNL YELSAFFHGM VMIQSIANLK RSSFAIPELR TKYFDWAYSI IHRGVDSYAV
HILLFSNHLT FSPLDIRNFG INALSGSIPK EFGNLTNLIS LGLGSNNFSG PLPSELGNLD
KLTGLWASDN NFTGKIPDYI GSWNLTDLRF QGNSFQGSIP ATLSKLVQLT NLRIGDIENG
SSSLAFISNM TSLSILDFSY NQLSGNFPSW ANEKNLQLNL VANNFVLDNS NNSVLPSGLE
CLQRNTPCFL AASFAVNCGS NRSISGSDNY VYQADGVSLG AAQYYVTGET KWGVSNVGKF
MDAPSNGIYI FNSSRQFQST LDPELFQTAR LSPSSLRYYG IGLENGNYTV TLQFAEIEFE
DTKSWKSLGR RVFDIYIQGE RKERNFDIRK ATGGKSYTAV KKQYLIPVTK NFVEIHLFWA
GKGTCCIPAQ GYYGPSISAL SLKPTLAAIF LWMQKRRKLS LEQQELYCIV GRPNVFSYGQ
LRSATENFNF SNRLGEGGYG AVYKGKLTDG RVVAVKQLSQ TSNQGKQQFA TEIETISRVQ
HRNLVKLYGC CLEGKHPLLV YEYLENGSLD KALFGTEKLN IDWPARFEIC LGIARGLAYL
HEESSIRVIH RDIKASNVLL DANLNPKISD FGLAKLYDDK KTHVSTKVAG TFGYLAPEYA
MRGRMTEKVD VFAFGVVLLE ILAGRPNYDD ALEEDKIYIF EWAWDLYENN NPLGLVDPKL
EEFNREEVLR AIRVALLCTQ GSPHQRPPMS RVVTMLAGDV EAPEVVTKPS YITEWQLKGG
DTSYLDSELA VELGAGRTGL AADLVAVLEL RRLGWRLHCR HRLAAHRFSS PGRGGEVSRR
KMGWRMAVSR LLHGCVLVLL LAAAVVQAQQ AATRTDPTEA AALNAVFAKL GQQAQSSWNL
SGDPCTGRAT DGSAIDDTSF NPAITCDCTF QNSTICRITK LKIYAVDASG QIPEELRNLT
RLTDLTFGIN SLSGPIPKEL GNLTNLISLY IDSAGLSGPL PSSLSKLTRM QILWASDNNF
TGQIPDYIGS WNLTDLRFQG NSFQGPIPAA LSNLVQLSSL RIGDIENGSS SSLAFISNMT
SLSILILRNC RISDDLASLD FSKFASLSLL DLSFNNITGE VPATLLASSF AVNSGSNRFI
SGSDNLRYET DGVNLRAASY YVTGAPTWGV SNVGKFMDAP NGSYIIYSSR QFQNTLDSEL
FQTSRMSPSS LRYYGIGLEN GNYTVTLQFA EFGIEDTQSW KSLGRRGERK EKNFDIRKTA
GDKSYTVVKK QYKVPVTKNF LEIHLFWAGK GTCCIPTQGY YGPTISALSV IPADFTPTVG
NTAQKNKSTS KTGVIVGVVV GVMVLGLVAL VGIFMWRQKR RKLSLEQQEL YSIVGRPNVF
SYSELRSATE NFSSSNRLGE GGYGAVYKGK LTDGRVVAVK QLSQTSHQGK KQFATEIETI
SRVQHRNLVK LYGCCLEGNN PLLVYEYMEN GSLDKALFGT EKLTIDWPER FEICLGIARG
LAYLHEESSI RVVHRDIKAS NVLIDANLNP KISDFGLAKL YDDKKTHVST KVAGTFGYLA
PEYAMRGHMT EKVDVFAFGV VLLETLAGRP NYDDTLEEDK IYIFEWAWEL YENNNPLGLV
DPKLKEFNRE EVLRAIRVAL LCTQGSPHQR PPMSRVVSML AGDVEVPDVL TKPSYITEWQ
IKGGNTSFAN SAVSGQSSSA PGSASEQQGS SLFLNSVIPE GRGQMVCETV TSLLPETEKR
GRRRAEGSRR ETMRVMSHLL LHGGVLLLLL AAAAVQAQRV ATKTDPTEAA ALNAVFAKLG
QQASLSTATW NISGDPCTGA ATDGTPIDDN PNFNPAIKCD CTFQNNTVCR ITKLKIYALD
VPGTIPQELR NLTRLTHLNL GQNTLTGPLP SFIGELTNMQ NMGLGSNRFN GSLPSELGNL
DKLQELYIDS AGLSGPLPSS FSKLTRMQTL WASDNDFTGQ IPDYIGNWNL TDLRFQGNSF
QGPIPSALSN LVQLSSLRIG DIENGSSSSL AFIGNMTSLS ILILRNCKIS DNLASIDFSK
FASLNLLDLS FNNITGQVPT ALLGLNLLNS LKPSKLKRTF TFNFEIFLHG LVGKIYNLSY
LQGLHAFKEI RHVFLVLHTS SFAVDCGSNR LISASDNLRY QTDDASLGPA SYSVTGAPTW
GVSNVGKFVD APNGSYIIYS SRQFQNTLDS ELFQTSRMSP SSLRYYGIGL ENGNYTVTLQ
FAEFGIEDTQ TWKSLGRRVF DIYLQGERQE KNFDIRKAAG DKSYTVVKKS YKVPVTKNFL
EIHLFWAGKG TCCIPGQGYY GPTISALSVT PAVLGLVALV GIFMWRQKRR KLTLEQQELY
SIVGRPNVFS YSELRSATEN FSSSNRLGEG GYGAVYKGKL NDGRVVAVKQ LSQTSHQGKK
QFATEIETIS RVQHRNLVKL YGCCLEGNNP LLVYEYMENG SLDKALFGIE KLNIDWPARF
DICLGIARGL AYLHEESSIR VVHRDIKASN VLLDANLNPK ISDFGLAKLY DDKKTHVSTK
VAGTFGYLAP EYAMRGHMTE KVDVFAFGVV LLETLAGRPN YDDTLEEDKI YIFEWAWELY
ENNNPLGIVD PNLREFNRAE VLRAIHVALL CTQGSPHQRP PMSRVVSMLT GDTEVTDVLM
KPSYITEWQI KGGNTSFANS AVRGQSSSAP GSTSQQASSV FLNSIIQEGR LSYCCYLHGC
LCVLVLLLCS WRAADAQAQQ PPPHTDPTEA AALNAMMARL GLSAPPSWNI SGDPCSGAAT
DDTPLDDNPA FNPAIKDFRK NYFTGPLPAF IGELTALKYI TVGINALSGP IPKELGNLTN
LVSLALGSNN FNGSLPDELG KLTKLQQLYI DSNDFSGPLP TTLSQLTNLS TLWALDNNFT
GQIPDYLGSL TNLTQLRLQG NSFQGPIPRS LYNLVKLRSF VLRNSRISDS LASVDFSKFG
SLNLLDLSFN NITGQIPPSI VNLPSLTFLN LVANDFVIDG TDMSGLPWGL NCLQRNTPCF
LAASFAVDCG GSRNISGSDN AMYQADNANL GAASYYVAGT PTWGVSTTGR FMDPPNGSYI
IYSSRQFDNT LDSGLFQTAR MSPSSLRYYG IGLENGNYTV TLQFAEVDFP DVQSWRSRGR
RIFDIYIQVA CKLTISLGER KEQNFDIRKA AGGKSFTVVK KQYVVPVTKN FLEIHLFWAG
KGTCCIPHQG YYGPAISALS ATPNFIPTVR SPADNKSRSK IAVIIVVMVG VAVFALAALA
GHFIWRQKKR KILLELEELY NIVGRPNVFS YNELRSATEN FSSSNLLGEG GYGLVHKGRL
SDGRAVAVKQ LSQSSNQGKK QFATEIETIS RVQHCNLVTL YGCCLESNTP LLVYEYLENG
SLDQALFGKG SLNLDWPTRF EICLGLARGI AYLHEDSTVR IVHRDIKASN ILGLPKLYDN
KKTHVSTKVA GTFGYLAPEY AMRGHMTEKV DVFAFGVVAL ETVAGESNYQ NTLEEDRAYI
FERVWELYEN GHPLDFVDPK LSEFNSEEVI RVIRVALLCT QGSPHKRPPM SKVVSMLTGD
ADITEDAAKP SYITEWQIKV GSCHHTGSSQ VGSASTPPSS GDGGAGQASS QGAGEGSPLT
PSPLFTSIID EGR
//
