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Database: UniProt
Entry: A0A0E0PS74_ORYRU
LinkDB: A0A0E0PS74_ORYRU
Original site: A0A0E0PS74_ORYRU 
ID   A0A0E0PS74_ORYRU        Unreviewed;       966 AA.
AC   A0A0E0PS74;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   31-JUL-2019, entry version 27.
DE   RecName: Full=Urease domain-containing protein {ECO:0000259|PROSITE:PS51368};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI05G30220.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|EnsemblPlants:ORUFI05G30220.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W1943 {ECO:0000313|EnsemblPlants:ORUFI05G30220.1};
RX   PubMed=22408737; DOI=10.1002/ece3.66;
RA   Waters D.L.E., Nock C.J., Rice N., Ishikawa R., Henry R.J.;
RT   "Chloroplast genome sequence confirms distinctness of Australian and
RT   Asian wild rice.";
RL   Ecol. Evol. 2:211-217(2012).
RN   [2] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:ORUFI05G30220.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Ni cation; Xref=ChEBI:CHEBI:25516;
CC         Evidence={ECO:0000256|PIRSR:PIRSR611612-51};
CC       Note=Binds 2 nickel ions per subunit.
CC       {ECO:0000256|PIRSR:PIRSR611612-51};
CC   -!- PTM: Carbamylation allows a single lysine to coordinate two nickel
CC       ions. {ECO:0000256|PIRSR:PIRSR611612-50}.
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DR   STRING; 4529.ORUFI05G30220.1; -.
DR   EnsemblPlants; ORUFI05G30220.1; ORUFI05G30220.1; ORUFI05G30220.
DR   Gramene; ORUFI05G30220.1; ORUFI05G30220.1; ORUFI05G30220.
DR   OMA; GFDSHIH; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:InterPro.
DR   GO; GO:0043419; P:urea catabolic process; IEA:InterPro.
DR   CDD; cd00375; Urease_alpha; 1.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_01953; Urease_alpha; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR011612; Urease_alpha_N_dom.
DR   InterPro; IPR017950; Urease_AS.
DR   InterPro; IPR005848; Urease_asu.
DR   InterPro; IPR017951; Urease_asu_c.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   InterPro; IPR040881; Urease_linker.
DR   InterPro; IPR029754; Urease_Ni-bd.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   Pfam; PF00449; Urease_alpha; 1.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   Pfam; PF18473; Urease_linker; 1.
DR   PRINTS; PR01752; UREASE.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF51338; SSF51338; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR01792; urease_alph; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   PROSITE; PS01120; UREASE_1; 1.
DR   PROSITE; PS00145; UREASE_2; 1.
DR   PROSITE; PS51368; UREASE_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008022};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00700};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR611612-51};
KW   Nickel {ECO:0000256|PIRSR:PIRSR611612-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022}.
FT   DOMAIN      500    966       Urease. {ECO:0000259|PROSITE:PS51368}.
FT   REGION        1     93       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     60     82       Basic. {ECO:0000256|SAM:MobiDB-lite}.
FT   ACT_SITE    691    691       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR611612-52, ECO:0000256|PROSITE-
FT                                ProRule:PRU00700}.
FT   METAL       505    505       Nickel 1; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       507    507       Nickel 1; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       588    588       Nickel 1; via carbamate group.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       588    588       Nickel 2; via carbamate group.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       617    617       Nickel 2; via pros nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       643    643       Nickel 2; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       731    731       Nickel 1. {ECO:0000256|PIRSR:PIRSR611612-
FT                                51}.
FT   BINDING     590    590       Substrate. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00700}.
FT   MOD_RES     588    588       N6-carboxylysine. {ECO:0000256|PIRSR:
FT                                PIRSR611612-50}.
SQ   SEQUENCE   966 AA;  104170 MW;  44C974B203B76D86 CRC64;
     MAARGPEMGE SDPHAAAVLR DGDGSGGRRC SATAERGEKA EVALLSDGDD GGGGGGGGAA
     KGRRRRRQKR GASRRGRRWR RSKGKAAAAE VDGAAAAQKR EEFSLSVRPA NATYIYRISP
     PEFAIPIGDH SNRMKLVQRE AEKLALHNAG FLAQKRLARG LRLNYTEAVA LIAAQILEFV
     RDGDRTVTDL MDLGKQLLGR LSILISILVS LTEGFVCVPS LEKFSSVGVD DFPGEVRFCS
     GHIVLNLHRR ALTLKVVNKA DRPIQIGSHY HFIEANPYLV FDRQRAYGMR LNIPAGTAVR
     FEPGDAKTVT LVSIGGRKVI RGGNGIADGA VNRSQLNEVM EKVIANGFGH EDYPDSSEGI
     IGDGTHDYSV DHEKYASMYG PTTGDKIRLG DTDLFAEIEK DYAIYGDECI FGGGKVLRDG
     MGQSAGYPAS DCLDTVVTNA VVIDYTGIYK ADIGINGGLI VAIGKAGNPD VMDMDGVNEE
     MIVGVNTEVI AAEGMIVTAG GIDCHVHFIC PQLAEEAIAS GITTLVGGGT GPAHGTCATT
     CTPSPSHMKL MLQSTDELPI NMGFTGKGNT TKPDGLAEII KAGAMGLKLH EDWGSTPAAI
     DNCLSVAEAF DIQVNIHTDT LNESGCVEHT IAAFKDRTIH TYHSEGAGGG HAPDIIKVCG
     VKNVLPSSTN PTRPFTLNTV DEHLDMLMVC HHLDRNIPED VAFAESRIRA ETIAAEDILH
     DMGAISIISS DSQAMGRIGE RLFINCPNNV RVPCKCEVIT RTWQTANKMK RQRGRLPISS
     SPDAAEDNDN FRIRRYIAKY TINPAIVNGF SDFVGSVECR VKATRRWSYR AVWSVWKLVY
     FSCIQPINVG KLADLVIWKP SFFGAKPEMV MMRPMFGAFG GAGSANSIAF VSKAAKEAGV
     AVQYKLGKRV EAVGRVRGLT KLNMKLNDAL PKIDVDPETY TVTADGEVLR CQPTPTVPLS
     RNYFLF
//
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