ID A0A0E0QCI4_ORYRU Unreviewed; 1560 AA.
AC A0A0E0QCI4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA polymerase zeta catalytic subunit {ECO:0000256|ARBA:ARBA00021589};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI07G26670.3, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI07G26670.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC {ECO:0000256|ARBA:ARBA00005755}.
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DR EnsemblPlants; ORUFI07G26670.3; ORUFI07G26670.3; ORUFI07G26670.
DR Gramene; ORUFI07G26670.3; ORUFI07G26670.3; ORUFI07G26670.
DR HOGENOM; CLU_000203_3_0_1; -.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0016035; C:zeta DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0019985; P:translesion synthesis; IEA:InterPro.
DR CDD; cd05778; DNA_polB_zeta_exo; 1.
DR CDD; cd05534; POLBc_zeta; 1.
DR Gene3D; 1.10.132.60; DNA polymerase family B, C-terminal domain; 1.
DR Gene3D; 3.30.342.10; DNA Polymerase, chain B, domain 1; 1.
DR Gene3D; 1.10.287.690; Helix hairpin bin; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR042087; DNA_pol_B_thumb.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR InterPro; IPR030559; PolZ_Rev3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR025687; Znf-C4pol.
DR PANTHER; PTHR45812; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR45812:SF1; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR Pfam; PF00136; DNA_pol_B; 1.
DR Pfam; PF03104; DNA_pol_B_exo1; 1.
DR Pfam; PF14260; zf-C4pol; 1.
DR PRINTS; PR00106; DNAPOLB.
DR SMART; SM00486; POLBc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 716..896
FT /note="DNA-directed DNA polymerase family B exonuclease"
FT /evidence="ECO:0000259|Pfam:PF03104"
FT DOMAIN 963..1400
FT /note="DNA-directed DNA polymerase family B
FT multifunctional"
FT /evidence="ECO:0000259|Pfam:PF00136"
FT DOMAIN 1459..1532
FT /note="C4-type zinc-finger of DNA polymerase delta"
FT /evidence="ECO:0000259|Pfam:PF14260"
FT REGION 479..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1560 AA; 173165 MW; AE64A969D82C29A2 CRC64;
MAAAASSSSP PGTASPVLSV RIVSLDYYMA PPLPGFDFSY SHFHGGEVEE VPVIRIYGST
PAGQKTCLHI HRVLPFLYVP CKEDLHNVEK GNSFISGLLS DLEKALQIRS SSKKKHDGAV
LNRVFQPYES HIPYLLHFLI DYNLYGMGYV HVTDFKFRPP LPDDFHPKSS LHSKVDCSTE
SGHKVHPDNV AIRKPTIWIS STVPHSLILA SSATSHCMEG TNWNVTNRHS SLMLEADSRI
EGILNEKYKM YTSLSQATAD SKIVRSLLSI WEELEHLRLL EEAKPVDMGR PLRDSVLRSF
LHGIKYETAL SMLCPKEEVS YHRVPTMEES EKLEECLKSL NDIIGTITFS QNDYCSIIDS
DISAGTQQEN QITNVLCLEP SEEGNTQCPV SSSAAQRTSS QLFEEHEKLV DAEALGLLSW
LASSQAAEEP TTDDELVNEA ILSPLFSKKS IAVALESAQL DFDGASQQEC QDILDSIGPV
IGEEQPNDQM SYRSSVRLGE SSSLSNSIPQ IDGSSDENKE VPQEDGKYKI NRKRAGLPSY
SSPQSSSKAS KRGGNELLWG SLPLSIKKRS DLNADGHSGG AMPTEKVLSA SFMSGTGKNS
HANPDNTERG SSSPTGEHDP LCDSVRDLMR RRRRSFRSEQ SEVGNSGDAA YIVRKENEIV
NSERLELHDI SSDLSNSEMY YSGSEYLQMT FARKPPMKNE VFCLEGSSAE SRGELRPDPR
FDAINAVSLA VEDDADNTIE VHVLIRGNND SSHRRRNLDG VSGCDVNVFP GERELLNHLI
NAICSIDPDI IVGWEIQLGS LGFLAERAAH LGIGLLKRIS RTPPHQMKHP PMNPVDESSQ
ELPGASSADD VIDDASENNW SHAHASGIHV DGRIILNLWR LMRAEVKLNN YSLEAVANEV
LRRKVPLVPT KILNRWFATG SGRGRYRCIE YVNKRSSLNL EILNQLDLVN RTSELARVFG
IDFFSVLSRG SQFRVESMLL RLAHTQNYLA ISPGNQQVAS QPAMECLPLV MEPESAFYSD
PVVVLDFQSL YPSMIIAYNL CYSTCLGKVF PSKSSVLGVS SYSADPQKIA DLKNQLLLTP
NGVLYVQPEV RKGVLPRLLE EILSTRIMVK KAMKKLSASQ KVLQRIFNAR QLALKLIANV
TYGYTAAGFS GRMPCAEIAD SIVQCGRRTL ETAISFVNQH PLWKARVVYG DTDREEAFRI
GKEIASSITA MNPDPVTLKF EKVYHPCFLL TKKRYVGYSY ESPEQKEPIF DAKGIETVRR
DTCPAVAKIL EQSIRIMFEE QDLAKVRSYL ERQWTRILSG KISIQDFVFT KEVRLGTYSA
RASSLPPAAI VATKAILSDP RAEARYGERV PYVVIHGEPG ARLVDMVIDP YGLLEVGSPY
RLNALYYITK QIIPALQRVF GLVGADLNKW FNEMPRPIRE TLAKRQSASG HGSFSRLGLN
KKGVGKGSRI DTYYMSSHCI ICGEIIQGSD TFCNNCLRNE AVVGTVVAGR TSKLEREIQH
LAAICGHCGG ADWIVESGIK CISLACPVFF ERRKIQRELR GVSESAIEAG YYPFCCPELF
//
