ID   A0A0E0QR24_ORYRU        Unreviewed;       246 AA.
AC   A0A0E0QR24;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Vacuolar iron transporter 1.2 {ECO:0008006|Google:ProtNLM};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI09G10010.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI09G10010.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CCC1 family.
CC       {ECO:0000256|ARBA:ARBA00007049}.
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DR   AlphaFoldDB; A0A0E0QR24; -.
DR   SMR; A0A0E0QR24; -.
DR   STRING; 4529.A0A0E0QR24; -.
DR   EnsemblPlants; ORUFI09G10010.1; ORUFI09G10010.1; ORUFI09G10010.
DR   Gramene; ORUFI09G10010.1; ORUFI09G10010.1; ORUFI09G10010.
DR   eggNOG; KOG4473; Eukaryota.
DR   HOGENOM; CLU_038957_0_2_1; -.
DR   OMA; QMCCVGG; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:EnsemblPlants.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR   GO; GO:0006880; P:intracellular sequestering of iron ion; IEA:EnsemblPlants.
DR   CDD; cd02435; CCC1; 1.
DR   InterPro; IPR008217; Ccc1_fam.
DR   PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR   PANTHER; PTHR31851:SF86; VACUOLAR IRON TRANSPORTER 2; 1.
DR   Pfam; PF01988; VIT1; 1.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|ARBA:ARBA00022496};
KW   Iron {ECO:0000256|ARBA:ARBA00022496};
KW   Iron transport {ECO:0000256|ARBA:ARBA00022496};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022496}.
FT   TRANSMEM        160..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   246 AA;  26161 MW;  C6B1506441FAB736 CRC64;
     MVKEFVQDEE KQRLLLDEHT EKHFTAGEVV RDIIIGVSDG LTVPFALAAG LSGANAPSAL
     VLTAGLAEVA AGAISMGLGG YLAAKSDADH YHRELQREQE EIDTVPDTEA AEIADILSQY
     GLGPEEYGPV VNSLRSNPKA WLEFMMKFEL GLEKPEPRRA LMSAGTIALA YVVGGLVPLL
     PYMFVPTADR AMATSVVVTL AALLFFGYVK GRFTGNRPFI SAFQTAVIGA LASAAAFGMA
     KAVQSI
//