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Database: UniProt
Entry: A0A0E1RV19_COCIM
LinkDB: A0A0E1RV19_COCIM
Original site: A0A0E1RV19_COCIM 
ID   A0A0E1RV19_COCIM        Unreviewed;       263 AA.
AC   A0A0E1RV19;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   08-MAY-2019, entry version 18.
DE   SubName: Full=PAP2 domain-containing protein {ECO:0000313|EMBL:EAS27578.2};
GN   ORFNames=CIMG_10183 {ECO:0000313|EMBL:EAS27578.2};
OS   Coccidioides immitis (strain RS) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Coccidioides.
OX   NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS27578.2, ECO:0000313|Proteomes:UP000001261};
RN   [1] {ECO:0000313|Proteomes:UP000001261}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J.,
RA   Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E.,
RA   Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M.,
RA   Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J.,
RA   Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens
RT   Coccidioides and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
RN   [2] {ECO:0000313|Proteomes:UP000001261}
RP   GENOME REANNOTATION.
RC   STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
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DR   EMBL; GG704915; EAS27578.2; -; Genomic_DNA.
DR   RefSeq; XP_001239161.2; XM_001239160.2.
DR   EnsemblFungi; EAS27578; EAS27578; CIMG_10183.
DR   GeneID; 4558122; -.
DR   KEGG; cim:CIMG_10183; -.
DR   EuPathDB; FungiDB:CIMG_10183; -.
DR   KO; K07252; -.
DR   OMA; YATLIWS; -.
DR   OrthoDB; 1312138at2759; -.
DR   Proteomes; UP000001261; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd03382; PAP2_dolichyldiphosphatase; 1.
DR   InterPro; IPR039667; Dolichyldiphosphatase_PAP2.
DR   InterPro; IPR039666; Dolpp1/Cax4.
DR   InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR   InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR   PANTHER; PTHR11247:SF1; PTHR11247:SF1; 1.
DR   Pfam; PF01569; PAP2; 1.
DR   SMART; SM00014; acidPPc; 1.
DR   SUPFAM; SSF48317; SSF48317; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001261};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     26     50       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    124    143       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    192    209       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       56    207       acidPPc. {ECO:0000259|SMART:SM00014}.
SQ   SEQUENCE   263 AA;  29735 MW;  828E4DB2A286412A CRC64;
     MDNNKIDTPL ASFSLTHVHY NPEDPLSYLC AFLSLVPQAI VVVYVALIWA SREVEVLFMF
     AGQILCEALN FGLKRVIRQE RPQRTLPQNL SLLRFLSIWK FISAPAKRQP SLEVYGKGYG
     MPSSHSQFVA FFAFSVALFL LVRHKPTSSS TLPNDSPSTL TERVILSLLA FSGAAAVASS
     RIYLNYHTPK QVMVGIAAGI AFSVVWYLFG THLRRSGWID WLLEVRMAKL LRMRDLLIGE
     DLAEAGWQRW KVKRGQSVVK KFE
//
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