ID A0A0E1RX74_COCIM Unreviewed; 720 AA.
AC A0A0E1RX74;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE SubName: Full=CHY zinc finger domain-containing protein {ECO:0000313|EMBL:EAS31712.2};
GN ORFNames=CIMG_07191 {ECO:0000313|EMBL:EAS31712.2};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS31712.2, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704912; EAS31712.2; -; Genomic_DNA.
DR RefSeq; XP_001243295.2; XM_001243294.2.
DR AlphaFoldDB; A0A0E1RX74; -.
DR STRING; 246410.A0A0E1RX74; -.
DR GeneID; 4561270; -.
DR KEGG; cim:CIMG_07191; -.
DR VEuPathDB; FungiDB:CIMG_07191; -.
DR InParanoid; A0A0E1RX74; -.
DR OMA; STKCDCP; -.
DR OrthoDB; 325136at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16464; RING-H2_Pirh2-like; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039512; RCHY1_zinc-ribbon.
DR InterPro; IPR008913; Znf_CHY.
DR InterPro; IPR037274; Znf_CHY_sf.
DR InterPro; IPR017921; Znf_CTCHY.
DR InterPro; IPR037275; Znf_CTCHY_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR21319:SF0; AND RING FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08900)-RELATED; 1.
DR PANTHER; PTHR21319; RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF05495; zf-CHY; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF14599; zinc_ribbon_6; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF161219; CHY zinc finger-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF161245; Zinc hairpin stack; 1.
DR PROSITE; PS51266; ZF_CHY; 1.
DR PROSITE; PS51270; ZF_CTCHY; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00601}.
FT DOMAIN 297..364
FT /note="CHY-type"
FT /evidence="ECO:0000259|PROSITE:PS51266"
FT DOMAIN 366..432
FT /note="CTCHY-type"
FT /evidence="ECO:0000259|PROSITE:PS51270"
FT DOMAIN 433..475
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..712
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 80440 MW; F16EBC52E97CE7E4 CRC64;
MQSLPSNQAE SKSRDASPEV IQPRNENNNH DAPENVNDLE SVSVRATESG LPFPQFELSL
PWPSSSSESL QSSRSHDRYL SRRQSGILSN STRSGIYHAL QQNDEPRSML AGASWDESSA
MTTLLQSRIA TDGDDLIGDG NLGLTVENER WIDNGQSLPA DDGMRILRQR IHAIREGGAS
NAEKAQQIHA IMTESYRSSL GVSGSPQPTL QRGATIQPHD RPWTPLSPRS KHSSDQLTLT
PASTSSIASY TSGNPYYLSM DDLTPTYYPG TATLAQPYDH DDFVLSALAA GDLLDEEAQQ
ILGCKHYKRN VKLQCFTCKK WYTCRFCHDD IEDHTLIRRK TENMLCMMCQ TPQQANQWCK
SCGTQAACYY CGICKLWDND ASKSIYHCHD CGICRRGEGL GKDFFHCKTC SVCLPIKIET
SHRCIERATQ CDCPICGEYM FTSPDPVIFM KCGHSIHQKC FDKYSKTSYR CPICNKTVAN
MEAHFRNLDR TIGSQPMPAE FRNTKAVINC NDCHAKSVVQ YHWLGLKCDT CDSYNTSQIR
LFSTNNDQND EPVSRQGSGI LISIPRIPND LSVENRTIAR SIPTADGSSD ALGSIMGSGS
RAIPALPQSY NARSVSPTVS NYFGLSRRRG SIWTTISQPE VIHSDSENDE RGSFWPVSAL
KRATLGFLGS REYDSEEEKD DDEEQDDYED EDPANDQEEE LEDGEDDEDI DDIIDIFGHR
//
