ID A0A0E1RY05_COCIM Unreviewed; 760 AA.
AC A0A0E1RY05;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
GN ORFNames=CIMG_03013 {ECO:0000313|EMBL:EAS31989.2};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS31989.2, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704916; EAS31989.2; -; Genomic_DNA.
DR RefSeq; XP_001243572.2; XM_001243571.2.
DR AlphaFoldDB; A0A0E1RY05; -.
DR STRING; 246410.A0A0E1RY05; -.
DR GeneID; 4563134; -.
DR KEGG; cim:CIMG_03013; -.
DR VEuPathDB; FungiDB:CIMG_03013; -.
DR InParanoid; A0A0E1RY05; -.
DR OMA; GGHLMIQ; -.
DR OrthoDB; 2102523at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46462; UPSET, ISOFORM A; 1.
DR PANTHER; PTHR46462:SF3; UPSET, ISOFORM A; 1.
DR Pfam; PF20826; PHD_5; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 684..733
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 82745 MW; B7536EA8356D6094 CRC64;
MNWDHPIHSF TDPNVEPQTP TRTPTVHSFD DTAFQTPKFE SSFYDPRITW NTADPYASSP
ELSKAAHRFD QTPNQRAQNP LDPTISRHRQ IDHATRAIGS DDASTDHGTA VTDSIDSAKR
SAASMQTPPP TSTIRRKNQD RSNNANLNLS TPVQPTYTGQ PLETPSRVVG FSPGLFGLQD
SPDLFNLSSN PTTASPFFSR HQMPWNHESN AAEAAMDISD AYGDPFGPSN PAALDIFEPT
RVGDTNLDTL QLPVVHGSAA LDSRAMAHEP CTLEASHAAL HSSIATSPRP PPLHGEDPSM
FLSSPARRFG YSEPTFSPPL RPRVETRQPY HYQTEVSERE RRDKELKRLH RPKSSSRRQK
TARVESASYV PQGATGKPIV KRSATHSGAP PLSSSRHQRQ SSFSSAGPVI GGGGVKKTPS
KGRTSPLKTQ LTPLAHPPPA SLPAPMESLV LKISKDGLAT TEMKLISDSP TRLRPGLRDT
VSGESSTEIE SDSSDEEPDY MIAHSQNPSF AFPDNTLRRP DFVRAQSTSR PHSKGSSYSS
AAASSHSGQL SPWTGSTHSR QSQLSSQPES RNQKRHPTQP GPSHSRSQSM TDSDATYEED
GAGDAQHALM QVLKGRKRQS RPPVTGKQLA TSSFRPSTIS TMRSSPPSYG TRPLSRPASS
NSPTVTDPAP PTPAADRQNN PSTGTRCVCN SMNNGGHLMI QCDTCAHWLH TKCVGLDRQR
LPPVYVCVYC TQTPSRGLRL REPFSISNSS PLARKLYGGR
//
