ID A0A0E1S4R8_COCIM Unreviewed; 1865 AA.
AC A0A0E1S4R8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 28-JUN-2023, entry version 31.
DE SubName: Full=Cellular morphogenesis regulator DopA {ECO:0000313|EMBL:EAS35703.1};
GN ORFNames=CIMG_01057 {ECO:0000313|EMBL:EAS35703.1};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS35703.1, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the dopey family.
CC {ECO:0000256|ARBA:ARBA00008395}.
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DR EMBL; GG704911; EAS35703.1; -; Genomic_DNA.
DR RefSeq; XP_001247286.1; XM_001247285.2.
DR STRING; 246410.A0A0E1S4R8; -.
DR GeneID; 4567518; -.
DR KEGG; cim:CIMG_01057; -.
DR VEuPathDB; FungiDB:CIMG_01057; -.
DR InParanoid; A0A0E1S4R8; -.
DR OMA; GLETCIA; -.
DR OrthoDB; 23089at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040314; DOP1.
DR InterPro; IPR007249; Dopey_N.
DR PANTHER; PTHR14042; DOPEY-RELATED; 1.
DR PANTHER; PTHR14042:SF24; PROTEIN DOPEY-1 HOMOLOG; 1.
DR Pfam; PF04118; Dopey_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 36..362
FT /note="Dopey N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04118"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1456..1476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1865 AA; 208357 MW; B7A15580CA46FDB6 CRC64;
MSLDPASLAR SSSPASSEAS LPKNQSRAYE DGLKKDKAYR RYASNVERAL SLFDTTLQEW
ADYISFLSRL LKALQSHPLS LAVVPEKVIV AKRLAQCLNP SLPSGVHQKA LEVYGYIFAL
LKPDGLARDL SLYLPGIAPT LTFASLSVRP LFLSLVETYI AHLDAACIRP ALKAILLSLL
PGLEEETSED FETTLRIVNR FRDISSEVKG NISASDSHAG SQYFWQCLFL ASITSPTRRM
GVLAYLNRYF PKLGGHAPWA APLNQAHPEE ETEISASIAS LTSPEPGLLI RCFATGLADD
QLLVQRNYLD VLVTHLPLHS PVLQTRISAD DLELLVAAAA GVVIRRDMSL NRRLWTWFLG
PDLAQNSDEN GDSDLKSITS GRSMFPSEKG IPKSKYFARF GLVPLVNSIK GMIARKYTVP
QERAKPFRIS LSLMDRWEVG GLIVPEIFLP VLRNVQEYYR VATPKAFDEV LRSASAFFDG
VESSLIFSEL LTLVLDMNQD VSDKVLGNLR LARFAISHFN IKEEEMLTIH IPLLLLGTLL
TMKTLSSTKE NSEISKSAFD EASWIAHHLL GLIPGRAFIQ KPQGNQSHHQ MIMTAENMTL
DEISLQLHRF YAITKESLDD PEPPFTPKIL AELLICEAHS QVIDALKAEK PHTRPKDQIN
FLLSLLKKVP LSQIFESGEL YLAMYEKVSV AKGQLSMTTL SAICSIVTTL YSTHETGSYI
SYGQICDIVP YLVQQLWEFL SPLSPVFHVE AVRCFWLLHS ISWNDRIVEA AITSLMIPST
TSSFSHRTSV DRVEKFFVLW NHSYQAGSSR SASRVIWEYP FDQTPGRDSQ SAYRLSLLER
PLFISLDLLA SGPGRAYSMV KQWVQDPSTA YHVLDILTSK LSEFQYFRPD ISIPSGIDAK
AGLDDGDQCL YLFKAVLNTI LALNHAGWSA LTSKISPNCS KQALQTDVED RSSLQSTIAQ
LSVRVLKERQ QISTNMGLRG EDLQEVALFV LHQLLLGPGA DSLYPLSLDT ILIEQLSSCL
DRNETTLQSA IIDAILPSLK IRFAHDTREL SAAMASKNQH RRSSLEALSN ISRLSFTGER
SEKDYIISQL PQPPSQLLDC LLKGIRAKSS RPMIDKWVHF LTECLPLYLG VIFQVLLKLV
ECLCKEINQS YKELQLMFQQ TESASRNRSE HVTIALLTAL ENCIATAHDR LLLEESHGSA
TKTPDQPQSF FGNMVSGVFT AEASQPRSAT ANDRLTVLLC FQDAVRLCYS IWAWGDSGRG
KDTRDSDCQA SFQYTSLRMR NRSRRILEHL FTAETLECLE TLIDLWRTSL RGGNRISGRS
VFNLLHTLEG SRPKVAIPAV FNAIYSRTNP AALDPSRKSA MMSHLTEAEL AAFLVMYARS
LDEDVLDEIW LDCTTFLRDV LSNPFPHRQI LSRLLEFAAI LGEKMEHTTF GEDQRAKRDL
GDILLRLLTA ISTSKPIGAS QDQSPKSRAV QNPDNQVSSL SKDLVIGPDD VYSILSSIMP
ALTTSFDADR IASAMSNIST NILAPLFHSR LFPQNINKTM LDILQQMSKI PSASRYWRKD
VGDALNDPKF FGMKLNLVKS NWLGLLRQWT LTDKERLPEL LSRLSQPSSA GIMFGVGASA
ARLEADRKSQ LNLRRIALLI LAADEDHFSG DLSGLQQKLE DLLAATHISS PSSATRAEVY
MVLRALVLKT STIHLAPFWP LINTELQEVV YTIAPGRESE TYNPYCLLQA CKLLETLLLT
SPDDFQLQEW LFVTDTIDII YPPDRWEAVA LADEIALALG TTKNGSTAHL HETGERDDEF
NRLWLGTDLS RETAKDEIVD RLLRPFFTRL SIHAFESTYS LGSPELLACQ DDLLADLFND
FTIAS
//
