ID A0A0E3KZQ3_9EURY Unreviewed; 316 AA.
AC A0A0E3KZQ3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=UDP-glucose 4-epimerase {ECO:0000313|EMBL:AKB23238.1};
DE EC=5.1.3.2 {ECO:0000313|EMBL:AKB23238.1};
GN ORFNames=MSWH1_2967 {ECO:0000313|EMBL:AKB23238.1};
OS Methanosarcina sp. WH1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434102 {ECO:0000313|EMBL:AKB23238.1, ECO:0000313|Proteomes:UP000033112};
RN [1] {ECO:0000313|EMBL:AKB23238.1, ECO:0000313|Proteomes:UP000033112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH1 {ECO:0000313|EMBL:AKB23238.1,
RC ECO:0000313|Proteomes:UP000033112};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; CP009504; AKB23238.1; -; Genomic_DNA.
DR RefSeq; WP_048129916.1; NZ_CP009504.1.
DR AlphaFoldDB; A0A0E3KZQ3; -.
DR GeneID; 24835888; -.
DR KEGG; mef:MSWH1_2967; -.
DR PATRIC; fig|1434102.4.peg.3874; -.
DR HOGENOM; CLU_007383_1_7_2; -.
DR Proteomes; UP000033112; Chromosome.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd05234; UDP_G4E_2_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 2.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:AKB23238.1}.
FT DOMAIN 7..242
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 316 AA; 34920 MW; 1E194E9F514B54C0 CRC64;
MPSKNRILVT GGAGFIGSNL VDRLLEKGNQ VIVFDNLSSG KMEFIEHHLE NPDFTLMKGD
LLDREAIESA CKGIDFVFHV AANPDVKLGA SDTKVHLDQN ILATYNLLET MRKGGAKRIA
FTSTSTIYGE ASIMPTPEDY GPLIPISLYG ASKLACEALI TSYSHTFDMQ AWIFRFANIV
GPRSTHGITV DFIKKLTENP SRLEILGDGK QEKSYLHVSE CVDAILFAIE KSKKEVNIFN
IGSEDTISAT EIGKVIVEEM GLSDVEFTYT GGSRGWKGDV PRMRLEIEKL KAIGWKPAYT
SERSVRETAR ELFSGN
//
