ID   A0A0E3L756_9EURY        Unreviewed;       676 AA.
AC   A0A0E3L756;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Bipolar DNA helicase {ECO:0000313|EMBL:AKB26186.1};
GN   ORFNames=MSMTP_2717 {ECO:0000313|EMBL:AKB26186.1};
OS   Methanosarcina sp. MTP4.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=1434100 {ECO:0000313|EMBL:AKB26186.1, ECO:0000313|Proteomes:UP000033049};
RN   [1] {ECO:0000313|EMBL:AKB26186.1, ECO:0000313|Proteomes:UP000033049}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MTP4 {ECO:0000313|EMBL:AKB26186.1,
RC   ECO:0000313|Proteomes:UP000033049};
RA   Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA   Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT   "Methanogenic archaea and the global carbon cycle.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP009505; AKB26186.1; -; Genomic_DNA.
DR   RefSeq; WP_048181014.1; NZ_CP009505.1.
DR   AlphaFoldDB; A0A0E3L756; -.
DR   STRING; 1434100.MSMTP_2717; -.
DR   GeneID; 24858161; -.
DR   KEGG; metm:MSMTP_2717; -.
DR   PATRIC; fig|1434100.4.peg.3628; -.
DR   HOGENOM; CLU_023282_0_0_2; -.
DR   Proteomes; UP000033049; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR30121:SF6; TYPE IV SECRETION SYSTEM PROTEIN CAGE; 1.
DR   PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:AKB26186.1};
KW   Helicase {ECO:0000313|EMBL:AKB26186.1};
KW   Hydrolase {ECO:0000313|EMBL:AKB26186.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:AKB26186.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033049}.
FT   DOMAIN          296..526
FT                   /note="Helicase HerA central"
FT                   /evidence="ECO:0000259|Pfam:PF01935"
FT   REGION          1..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..85
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   676 AA;  74633 MW;  29C495D7E3DE7EC6 CRC64;
     MKFEDADILA FASGKTKKTP APDKDEGAEK STGMEPKTGS ENSPTGSYRK GPDTFPEDPL
     ASVYGGAGGT GSGSGSSSGS GSDPVSGPGS DPEPADLPFE DFGGYDEGIA TPAASADEAF
     GIVTAGIDPL EITPAGATIT GYISSLRRNE IRLGAYVVVP YEGGEKLFAR VGKLQYRQEF
     AVDDATELHS RRMLGGRASP VNEDDYKFLA YLDPLCILYR KGQDTPLSRR MADRIPRPNT
     PILPVRDRLE VQTGLNIPEE GIFLGHLSVG GELVKTHSEP ETVAYYLRND YSMGDPLVFR
     HMLVCGSTGT GKTFLTKNIL RQFMTESNRY RLRNSPDDRA RKNPCLVIMD PQDEYSQIFE
     DNATLTEDDR FRFESEKVAY GRVPSTKAFV AKVEGQTYPG DKSRAEQHEF TIPFSLVEHN
     SWLIAATGMS ELQYIGLELL LGDFFKSSVP HTYLNFISHI DNEGTRSYYV DSGKLHEASY
     DGIVRRVKSR FFSKVFDQAA TPITEILDRI FKPGQISVFP TEYISTPRIR DLIVLTIMSL
     IVDNKLGTTG TDAIKNTPII LCLDEAHRYL SRAGGEHSRL IISRFADAAR QGRKEGLGLF
     LITQDPQDID DTVFKQVNTK LILNLNNDAA ISSLKVPKEY ERRIPYLKKG QMVVHSPDNS
     DIVEIIGLSK CVVKHQ
//