ID A0A0E3NRB8_9EURY Unreviewed; 1255 AA.
AC A0A0E3NRB8;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=N-methylhydantoinase A/acetone carboxylase, beta subunit {ECO:0000313|EMBL:AKB21860.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:AKB21860.1};
DE EC=3.5.2.9 {ECO:0000313|EMBL:AKB21860.1};
GN ORFNames=MSWH1_1589 {ECO:0000313|EMBL:AKB21860.1};
OS Methanosarcina sp. WH1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434102 {ECO:0000313|EMBL:AKB21860.1, ECO:0000313|Proteomes:UP000033112};
RN [1] {ECO:0000313|EMBL:AKB21860.1, ECO:0000313|Proteomes:UP000033112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH1 {ECO:0000313|EMBL:AKB21860.1,
RC ECO:0000313|Proteomes:UP000033112};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; CP009504; AKB21860.1; -; Genomic_DNA.
DR RefSeq; WP_048127727.1; NZ_CP009504.1.
DR AlphaFoldDB; A0A0E3NRB8; -.
DR GeneID; 24814149; -.
DR KEGG; mef:MSWH1_1589; -.
DR PATRIC; fig|1434102.4.peg.2036; -.
DR HOGENOM; CLU_002157_0_0_2; -.
DR Proteomes; UP000033112; Chromosome.
DR GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AKB21860.1}.
FT DOMAIN 12..191
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 210..530
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 546..708
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 730..1235
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
FT REGION 239..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1228..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1233..1255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1255 AA; 137775 MW; 1C461D1E043CB1A5 CRC64;
MFSQPQKARW QFWIDRGGTF TDLVARSPDG KLITHKLLSE DPAHYKDAAM HGIRQILGLP
KDASLPAELI EAVKMGTTVG TNALLERKGE RTVLAITKGF GDALRIGYQN RPDIFAQKIE
LPDQLYERVI EVSGRFRADG KELVVLDLES AKKELEAAYK AGIRSAAIVL MHAYRYPEHE
LKLGRLAREI GFTQVSLSHQ ASPLIKLVSR GETTVVDAYL SPVLRRYIDM IQKTLEERGA
EIEEKESEKE GSPEEKNPEE KYRGKNTPRL MFMQSSGGLI GADTFQGKDC ILSGPAGGIV
GAVATSEMAG AKKVITFDMG GTSTDVAQYS GEYERSLETE IAGVRLRSPM MRIHTVAAGG
GSILHYEGSR FRVGPDSAGS DPGPASYRKG GPLTVTDCNV MLGKLQPELF PKIFGPDGDQ
PLDSEIVRRK FSEIAKEVSE KEAVSGGSVR TPEQVAEGFL SVAVENMANA IKKISVQRGY
NIKEYTLCCF GGAGAQHACR VADSLGVKRI FIHPYAGVLS AYGMGLADQR LIKESYVGAE
LSDGLIEELK TVFARLENDS RLMMLEQGVQ EDCIAVLFKA HMRYAGSDTQ LAVDFADKDA
LRRGFEEAHK KRFGFVIEGK AMVIEAVSVE IIGITERVLD PLLKTETNPA FSPVLVVQMY
SYGEFHETPV FQRQELKPGT CISGPAIFIE KNTTIIIEPG WEGEITKRDH LLLHRKIPLP
THTAIGTEAD PVMLEIFNNR FMSVAEQMGY TLQNTAYSVN IKERLDFSCA IFDRYGNLIA
NAPHIPVHLG SMGECVKSLI RTQFQEMQAG DVYLINSPYH GGTHLPDITV VTPMFGSSGD
VLFYLASRGH HADVGGINPG SVPPGSRTIE EEGVLSEGMK IVKQSHFCEE KLRVWLNSGK
YPARNPDQNM ADLRAQVAAN EKGLQELRRM VEEFSLETVE AYMNHVQDNA EEAVRRVIDR
LSNGEFTYML DDGSAIKVKV TIDRKHRGAR IDFTGTSPQL SNNFNAPASV CLAAVLYTFR
TLVKSDIPLN AGCLRPLEII IPEGSMLKPE YPAAVVAGNV ETSQYIVDAL FGALGTMAAS
QGTMNNFTFG NSDFQYYETI CGGAGAGPGF SGTDAVHTHM TNSRITDPEI LETRFPVFLE
DFSIRQESGG EGKFRGGNGV IRKIRFLKDM HAAVLSSHRK LPPFGLNGGM PGECGKNTLI
RRDGRVMEVG GQAEIKLKNG DVFVIETPGG GGYGEKHKQE KKEQKSRNRN VSDLK
//
