ID A0A0E3NV29_9EURY Unreviewed; 358 AA.
AC A0A0E3NV29;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Tungsten-containing aldehyde ferredoxin oxidoreductase cofactor modifying protein {ECO:0000313|EMBL:AKB22884.1};
GN ORFNames=MSWH1_2613 {ECO:0000313|EMBL:AKB22884.1};
OS Methanosarcina sp. WH1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434102 {ECO:0000313|EMBL:AKB22884.1, ECO:0000313|Proteomes:UP000033112};
RN [1] {ECO:0000313|EMBL:AKB22884.1, ECO:0000313|Proteomes:UP000033112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH1 {ECO:0000313|EMBL:AKB22884.1,
RC ECO:0000313|Proteomes:UP000033112};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP009504; AKB22884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E3NV29; -.
DR KEGG; mef:MSWH1_2613; -.
DR PATRIC; fig|1434102.4.peg.3406; -.
DR HOGENOM; CLU_009273_4_2_2; -.
DR Proteomes; UP000033112; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR11228:SF34; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE COFACTOR MODIFYING PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 2.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 11..237
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 358 AA; 40777 MW; F83001203F2CBDC0 CRC64;
MYGAQEAHEA RNSNRLLAIR LETNTSCNLR CRYCYAQSGE DSVKIADFNV LKRIISEAKE
LGIRSVVVIG GGEPTLYPNF RELIACIDSL GIIPMLFTNT VLMTEELAGF LYEHNASVMG
KLDSLRPEVQ DYLAGREGAF DDIKIGLENL IKAGFSKPSE PGKLRLGISF VSNKMNLEEI
EVIWHFCRQN NIFPNMEILT PTGRANDELE DKLLTTDEIK EYKLKLLEID RKYYRYDWLP
YTPITASGCL QHLYSLYINI EGNVRPCAPT KLDEHPALRV NGEYPYNINR MSLREIYDSD
LFSYVRNIDK VLEGRCGNCE HTEECIGCRG YAYSVGINNG ADPLEALKME CKQCFKER
//
